[{"data":1,"prerenderedAt":238},["ShallowReactive",2],{"drug-meloxicam":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":12,"synonyms":16,"formulations":19,"regimens":42,"contraindications":99,"warnings":118,"renal":119,"monitoring":120,"interactions":121,"review":122,"examples":125,"atc":145,"iran":147,"links":171,"populations":191,"usApproval":233},"meloxicam",1,{"fa":7,"en":8},"ملوکسیکام","Meloxicam","musculoskeletal",{"fa":11,"en":11},"NSAID",[13],{"name":14,"market":15},"Mobic","US",[17,18,7],"mobic","موبیک",[20,34],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":29,"refs":30},"tab-7-5","tablet","oral","7.5 mg tablet",{"amount":26,"unit":27,"perUnit":22,"scored":28},7.5,"mg",false,[15],[31],{"source":32,"section":33},"fda-meloxicam","3",{"id":35,"form":22,"route":23,"label":36,"concentration":37,"markets":39,"refs":40},"tab-15","15 mg tablet",{"amount":38,"unit":27,"perUnit":22,"scored":28},15,[15],[41],{"source":32,"section":33},[43,62,77],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":55,"limits":58},"oa","osteoarthritis",{"fa":47,"en":48},"آرتروز — ۷٫۵ mg یک بار (تا ۱۵ mg)","Osteoarthritis — 7.5 mg once daily (up to 15 mg)",{"minAge":50},{"value":51,"unit":52},18,"year","fixed",{"perDose":26,"perDoseMax":38,"dosesPerDay":5},[56],{"source":32,"section":57},"2.2",{"maxPerDay":38,"refs":59},[60],{"source":32,"section":61},"2",{"id":63,"disease":64,"label":65,"population":68,"type":53,"unit":27,"dose":70,"refs":71,"limits":74},"ra","rheumatoid-arthritis",{"fa":66,"en":67},"آرتریت روماتوئید — ۷٫۵ mg یک بار (تا ۱۵ mg)","Rheumatoid arthritis — 7.5 mg once daily (up to 15 mg)",{"minAge":69},{"value":51,"unit":52},{"perDose":26,"perDoseMax":38,"dosesPerDay":5},[72],{"source":32,"section":73},"2.3",{"maxPerDay":38,"refs":75},[76],{"source":32,"section":61},{"id":78,"disease":79,"label":80,"population":83,"type":53,"unit":27,"dose":88,"refs":89,"notes":92},"jra","juvenile-arthritis",{"fa":81,"en":82},"آرتریت روماتوئید نوجوانان — ۶۰ kg به بالا: ۷٫۵ mg","Juvenile RA — ≥60 kg: 7.5 mg once daily",{"minAge":84,"maxAge":86,"minWeightKg":87},{"value":85,"unit":52},2,{"value":51,"unit":52},60,{"perDose":26,"dosesPerDay":5},[90],{"source":32,"section":91},"2.4",[93],{"text":94,"refs":97},{"fa":95,"en":96},"در کودکان زیر ۶۰ kg قرص استفاده نشود.","Do not use tablets in children under 60 kg.",[98],{"source":32,"section":91},[100,109],{"id":101,"severity":102,"text":103,"refs":106},"ci","block",{"fa":104,"en":105},"حساسیت به دارو؛ سابقه آسم، کهیر یا واکنش آلرژیک پس از آسپیرین یا NSAID؛ هنگام جراحی بای‌پس عروق کرونر (CABG).","Hypersensitivity; history of asthma, urticaria or allergic-type reaction after aspirin or other NSAIDs; in the setting of CABG surgery.",[107],{"source":32,"section":108},"4",{"id":110,"severity":111,"text":112,"refs":115},"boxed","warn",{"fa":113,"en":114},"هشدار جعبه‌ای: خطر حوادث قلبی‌عروقی ترومبوتیک و خونریزی، زخم و سوراخ‌شدگی گوارشی.","Boxed warning: risk of serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation.",[116],{"source":32,"section":117},"Boxed Warning",[],[],[],[],{"status":123,"reviewer":124,"date":124},"unverified",null,[126,130,135,139],{"regimen":44,"formulation":21,"input":127,"expect":129},{"ageYears":87,"weightKg":128},75,{"perDose":26,"upperPerDose":38},{"regimen":63,"formulation":21,"input":131,"expect":134},{"ageYears":132,"weightKg":133},50,70,{"perDose":26},{"regimen":78,"formulation":21,"input":136,"expect":138},{"ageYears":38,"weightKg":137},62,{"perDose":26},{"regimen":78,"formulation":21,"input":140,"expect":143},{"ageYears":141,"weightKg":142},12,40,{"status":144},"blocked",[146],"M01AC06",{"status":148,"forms":149,"refs":166},"registered",[150,154,158,162],{"code":151,"en":152,"fa":153},"07061","MELOXICAM 15MG TAB","قرص ملوکسیکام ۱۵ میلی‌گرم",{"code":155,"en":156,"fa":157},"05452","MELOXICAM 7.5MG TAB","قرص ملوکسیکام ۷٫۵ میلی‌گرم",{"code":159,"en":160,"fa":161},"53101","MELOXICAM TABLET, ORALLY DISINTEGRATING ORAL 15 mg","قرص بازشونده دهانی ملوکسیکام بازشونده ۱۵ میلی‌گرم",{"code":163,"en":164,"fa":165},"53100","MELOXICAM TABLET, ORALLY DISINTEGRATING ORAL 7.5 mg","قرص بازشونده دهانی ملوکسیکام بازشونده ۷٫۵ میلی‌گرم",[167],{"source":168,"section":169,"url":170},"darooyab-generic","G-125\u002FMeloxicam","https:\u002F\u002Fwww.darooyab.ir\u002FG-125\u002FMeloxicam",[172,176,180,183,186,189],{"kind":173,"url":174,"label":175},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=077921","ANDA077921",{"kind":177,"url":178,"label":179},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=58d34e5d-4efb-3d76-e063-6394a90aa0f6","FDA Meloxicam",{"kind":181,"url":182,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601242.html",{"kind":181,"url":184,"label":185},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa620024.html","Meloxicam Injection",{"kind":187,"url":188,"label":146},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=M01AC06",{"kind":190,"url":170,"label":8},"darooyab",{"pregnancy":192,"lactation":201,"pediatric":210,"geriatric":218,"reproductive":225},{"level":193,"text":194,"quote":197,"refs":198},"avoid",{"fa":195,"en":196},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Clinical Considerations Fetal\u002FNeonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including meloxicam, can cause premature closure of the fetal ductus arteriosus (see Data).",[199],{"source":32,"section":200},"8.1",{"level":202,"text":203,"quote":206,"refs":207},"caution",{"fa":204,"en":205},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no human data available on whether meloxicam is present in human milk, or on the effects on breastfed infants, or on milk production.",[208],{"source":32,"section":209},"8.2",{"level":202,"text":211,"quote":214,"refs":215},{"fa":212,"en":213},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of meloxicam in pediatric JRA patients from 2 years to 17 years of age has been evaluated in three clinical trials [see Dosage and Administration ( 2.3 ), Adverse Reactions ( 6.1 ) and Clinical Studies ( 14.2 )].",[216],{"source":32,"section":217},"8.4",{"level":202,"text":219,"quote":222,"refs":223},{"fa":220,"en":221},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly patients and patients with a prior history of peptic ulcer disease and\u002For GI bleeding are at greater risk for serious GI events ( 5.2 ) Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial …",[224],{"source":32,"section":117},{"level":202,"text":226,"quote":229,"refs":230},{"fa":227,"en":228},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including meloxicam, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.",[231],{"source":32,"section":232},"8.3",{"kind":234,"refs":235,"id":175},"ANDA",[236],{"source":32,"section":237},"SPL approval \u002F marketing category",1792440735304]