[{"data":1,"prerenderedAt":173},["ShallowReactive",2],{"drug-metronidazole-gel":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":33,"contraindications":49,"warnings":59,"renal":60,"monitoring":61,"interactions":62,"review":63,"examples":66,"atc":72,"iran":74,"links":125,"populations":140,"usApproval":168},"metronidazole-gel",1,{"fa":7,"en":8},"ژل مترونیدازول ۰٫۷۵٪ (پوستی)","Metronidazole 0.75% gel (skin)","dermatology",{"fa":11,"en":12},"ضدروزاسه موضعی","Topical anti-rosacea",[14],{"name":15,"market":16},"MetroGel","US",[18,19,20],"metrogel","مترونیدازول ژل پوستی","روزاسه",[22],{"id":23,"form":23,"route":24,"label":25,"concentration":26,"markets":28,"refs":29},"gel","topical","0.75% topical gel",{"amount":5,"unit":27,"perUnit":27},"application",[16],[30],{"source":31,"section":32},"fda-metrogel","How Supplied",[34],{"id":35,"disease":35,"label":36,"population":39,"type":43,"unit":27,"dose":44,"refs":46},"rosacea",{"fa":37,"en":38},"روزاسه — لایه نازک دو بار در روز پس از شستشو","Rosacea — thin film twice daily after washing",{"minAge":40},{"value":41,"unit":42},18,"year","fixed",{"perDose":5,"dosesPerDay":45},2,[47],{"source":31,"section":48},"Dosage and Administration",[50],{"id":51,"severity":52,"text":53,"refs":56},"hyper","block",{"fa":54,"en":55},"حساسیت به مترونیدازول یا پارابن‌ها.","Hypersensitivity to metronidazole or parabens.",[57],{"source":31,"section":58},"Contraindications",[],[],[],[],{"status":64,"reviewer":65,"date":65},"unverified",null,[67],{"regimen":35,"formulation":23,"input":68,"expect":71},{"ageYears":69,"weightKg":70},40,65,{"perDose":5},[73],"D06BX01",{"status":75,"forms":76,"refs":120},"registered",[77,81,85,89,93,97,101,105,109,112,116],{"code":78,"en":79,"fa":80},"02074","METRONIDAZOLE 0.75% VAG GEL","ژل واژینال مترونیدازول ۰٫۷۵ درصد",{"code":82,"en":83,"fa":84},"01590","METRONIDAZOLE 0.75%TOP GEL","ژل موضعی مترونیدازول ۰٫۷۵ درصد",{"code":86,"en":87,"fa":88},"12496","METRONIDAZOLE 200MG  TAB","قرص مترونیدازول ۲۰۰ میلی‌گرم",{"code":90,"en":91,"fa":92},"00845","METRONIDAZOLE 250MG TAB","قرص مترونیدازول ۲۵۰ میلی‌گرم",{"code":94,"en":95,"fa":96},"02162","METRONIDAZOLE 500MG OVULE","مترونیدازول ۵۰۰ میلی‌گرم اوول",{"code":98,"en":99,"fa":100},"12912","METRONIDAZOLE 500MG VAG SUPP","شیاف مترونیدازول ۵۰۰ میلی‌گرم",{"code":102,"en":103,"fa":104},"00846","METRONIDAZOLE 500MG VAG TAB","قرص واژینال مترونیدازول ۵۰۰ میلی‌گرم",{"code":106,"en":107,"fa":108},"00843","METRONIDAZOLE 500MG\u002F100ML VIAL P-BAG","ویال مترونیدازول ۵۰۰ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":110,"en":111,"fa":108},"08243","METRONIDAZOLE 500MG\u002F100ML VIAL P-BOTTLE",{"code":113,"en":114,"fa":115},"00844","METRONIDAZOLE BENZOATE 125MG\u002F5ML 120ML SUSP","سوسپانسیون مترونیدازول بنزوات ۱۲۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",{"code":117,"en":118,"fa":119},"51656","METRONIDAZOLE 500MG TAB","قرص مترونیدازول ۵۰۰ میلی‌گرم",[121],{"source":122,"section":123,"url":124},"darooyab-generic","G-1131\u002FMetronidazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-1131\u002FMetronidazole",[126,130,134,137],{"kind":127,"url":128,"label":129},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=218485","ANDA218485",{"kind":131,"url":132,"label":133},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2ced2460-a003-4314-897b-f4ae0ff72edf","FDA MetroGel vaginal",{"kind":135,"url":136,"label":73},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=D06BX01",{"kind":138,"url":124,"label":139},"darooyab","Metronidazole",{"pregnancy":141,"lactation":150,"pediatric":159},{"level":142,"text":143,"quote":146,"refs":147},"caution",{"fa":144,"en":145},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of human response, and because metronidazole is a carcinogen in rodents, this drug should be used during pregnancy only if clearly needed.",[148],{"source":31,"section":149},"Pregnancy: Teratogenic Effects:",{"level":151,"text":152,"quote":155,"refs":156},"avoid",{"fa":153,"en":154},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for tumorigenicity shown for metronidazole in mouse and rat studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[157],{"source":31,"section":158},"Nursing Mothers:",{"level":160,"text":161,"quote":164,"refs":165},"not-established",{"fa":162,"en":163},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in children have not been established.",[166],{"source":31,"section":167},"Pediatric Use:",{"kind":169,"refs":170,"id":129},"ANDA",[171],{"source":31,"section":172},"SPL approval \u002F marketing category",1792444704135]