[{"data":1,"prerenderedAt":197},["ShallowReactive",2],{"drug-metronidazole-vaginal":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":35,"contraindications":59,"warnings":79,"renal":80,"monitoring":81,"interactions":82,"review":83,"examples":86,"atc":92,"iran":94,"links":145,"populations":164,"usApproval":192},"metronidazole-vaginal",1,{"fa":7,"en":8},"ژل واژینال مترونیدازول","Metronidazole vaginal gel","genitourinary-sex-hormones",{"fa":11,"en":12},"نیتروایمیدازول موضعی واژن","Vaginal nitroimidazole",[14],{"name":15,"market":16},"MetroGel-Vaginal","US",[18,19,20,21],"metrogel","ژل واژینال","مترونیدازول واژینال","واژینوز",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":30,"refs":31},"gel-0-75","gel","vaginal","0.75% vaginal gel (5 g applicator)",{"amount":5,"unit":29,"perUnit":29},"application",[16],[32],{"source":33,"section":34},"fda-metrogel","Dosage and Administration",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":29,"dose":47,"refs":48,"durationDays":50,"notes":52},"bv","bacterial-vaginosis",{"fa":40,"en":41},"واژینوز باکتریایی — یک اپلیکاتور پر (۵ g) یک یا دو بار در روز، ۵ روز","Bacterial vaginosis — one applicatorful (5 g) once or twice daily for 5 days",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":5,"dosesPerDay":5},[49],{"source":33,"section":34},{"min":51,"max":51},5,[53],{"text":54,"refs":57},{"fa":55,"en":56},"هر اپلیکاتور حدود ۳۷٫۵ mg مترونیدازول.","Each applicator ≈ 37.5 mg metronidazole.",[58],{"source":33,"section":34},[60,69],{"id":61,"severity":62,"text":63,"refs":66},"ci","block",{"fa":64,"en":65},"حساسیت به مترونیدازول، پارابن‌ها یا سایر نیتروایمیدازول‌ها.","Hypersensitivity to metronidazole, parabens or other nitroimidazoles.",[67],{"source":33,"section":68},"Contraindications",{"id":70,"severity":62,"rule":71,"text":73,"refs":76},"child",{"maxAge":72},{"value":44,"unit":45},{"fa":74,"en":75},"در کودکان ثابت نشده.","Not established in children.",[77],{"source":33,"section":78},"Pediatric Use",[],[],[],[],{"status":84,"reviewer":85,"date":85},"unverified",null,[87],{"regimen":37,"formulation":24,"input":88,"expect":91},{"ageYears":89,"weightKg":90},28,60,{"perDose":5},[93],"G01AF01",{"status":95,"forms":96,"refs":140},"registered",[97,101,105,109,113,117,121,125,129,132,136],{"code":98,"en":99,"fa":100},"02074","METRONIDAZOLE 0.75% VAG GEL","ژل واژینال مترونیدازول ۰٫۷۵ درصد",{"code":102,"en":103,"fa":104},"01590","METRONIDAZOLE 0.75%TOP GEL","ژل موضعی مترونیدازول ۰٫۷۵ درصد",{"code":106,"en":107,"fa":108},"12496","METRONIDAZOLE 200MG  TAB","قرص مترونیدازول ۲۰۰ میلی‌گرم",{"code":110,"en":111,"fa":112},"00845","METRONIDAZOLE 250MG TAB","قرص مترونیدازول ۲۵۰ میلی‌گرم",{"code":114,"en":115,"fa":116},"02162","METRONIDAZOLE 500MG OVULE","مترونیدازول ۵۰۰ میلی‌گرم اوول",{"code":118,"en":119,"fa":120},"12912","METRONIDAZOLE 500MG VAG SUPP","شیاف مترونیدازول ۵۰۰ میلی‌گرم",{"code":122,"en":123,"fa":124},"00846","METRONIDAZOLE 500MG VAG TAB","قرص واژینال مترونیدازول ۵۰۰ میلی‌گرم",{"code":126,"en":127,"fa":128},"00843","METRONIDAZOLE 500MG\u002F100ML VIAL P-BAG","ویال مترونیدازول ۵۰۰ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":130,"en":131,"fa":128},"08243","METRONIDAZOLE 500MG\u002F100ML VIAL P-BOTTLE",{"code":133,"en":134,"fa":135},"00844","METRONIDAZOLE BENZOATE 125MG\u002F5ML 120ML SUSP","سوسپانسیون مترونیدازول بنزوات ۱۲۵ میلی‌گرم \u002F ۵ میلی‌لیتر ۱۲۰ میلی‌لیتر",{"code":137,"en":138,"fa":139},"51656","METRONIDAZOLE 500MG TAB","قرص مترونیدازول ۵۰۰ میلی‌گرم",[141],{"source":142,"section":143,"url":144},"darooyab-generic","G-1131\u002FMetronidazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-1131\u002FMetronidazole",[146,150,154,158,161],{"kind":147,"url":148,"label":149},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=218485","ANDA218485",{"kind":151,"url":152,"label":153},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2ced2460-a003-4314-897b-f4ae0ff72edf","FDA MetroGel vaginal",{"kind":155,"url":156,"label":157},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa617051.html","Metronidazole Vaginal",{"kind":159,"url":160,"label":93},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G01AF01",{"kind":162,"url":144,"label":163},"darooyab","Metronidazole",{"pregnancy":165,"lactation":174,"pediatric":183},{"level":166,"text":167,"quote":170,"refs":171},"caution",{"fa":168,"en":169},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of human response, and because metronidazole is a carcinogen in rodents, this drug should be used during pregnancy only if clearly needed.",[172],{"source":33,"section":173},"Pregnancy: Teratogenic Effects:",{"level":175,"text":176,"quote":179,"refs":180},"avoid",{"fa":177,"en":178},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for tumorigenicity shown for metronidazole in mouse and rat studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[181],{"source":33,"section":182},"Nursing Mothers:",{"level":184,"text":185,"quote":188,"refs":189},"not-established",{"fa":186,"en":187},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in children have not been established.",[190],{"source":33,"section":191},"Pediatric Use:",{"kind":193,"refs":194,"id":149},"ANDA",[195],{"source":33,"section":196},"SPL approval \u002F marketing category",1792444704384]