[{"data":1,"prerenderedAt":223},["ShallowReactive",2],{"drug-moxifloxacin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":87,"warnings":107,"renal":115,"monitoring":116,"interactions":117,"review":126,"examples":129,"atc":141,"iran":143,"links":163,"populations":183,"usApproval":218},"moxifloxacin",1,{"fa":7,"en":8},"موکسی‌فلوکساسین","Moxifloxacin","anti-infectives",{"fa":11,"en":12},"فلوروکینولون","Fluoroquinolone",[14],{"name":15,"market":16},"Avelox","US",[18,19,20],"avelox","آولوکس","موکسی فلوکساسین",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-400","tablet","oral","400 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},400,"mg",false,[16],[33],{"source":34,"section":35},"fda-moxifloxacin","3",[37,55,68],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":49,"durationDays":52},"cap","community-acquired-pneumonia",{"fa":41,"en":42},"پنومونی اکتسابی — ۴۰۰ mg روزانه، ۷ تا ۱۴ روز","CAP — 400 mg once daily, 7–14 days",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[50],{"source":34,"section":51},"2.1",{"min":53,"max":54},7,14,{"id":56,"disease":57,"label":58,"population":61,"type":47,"unit":29,"dose":63,"refs":64,"durationDays":66},"sinusitis","acute-bacterial-sinusitis",{"fa":59,"en":60},"سینوزیت باکتریایی حاد — ۴۰۰ mg روزانه، ۱۰ روز","Acute bacterial sinusitis — 400 mg once daily, 10 days",{"minAge":62},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":5},[65],{"source":34,"section":51},{"min":67,"max":67},10,{"id":69,"disease":69,"label":70,"population":73,"type":47,"unit":29,"dose":75,"refs":76,"durationDays":78,"notes":79},"plague",{"fa":71,"en":72},"طاعون (درمان یا پیشگیری) — بزرگسال ۴۰۰ mg یک بار در روز، ۱۰ تا ۱۴ روز","Plague (treatment or prophylaxis) — adult 400 mg once daily, 10–14 days",{"minAge":74},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":5},[77],{"source":34,"section":51},{"min":67,"max":54},[80],{"text":81,"refs":84},{"fa":82,"en":83},"تأیید طاعون بر اساس مطالعات حیوانی است (مطالعه انسانی ممکن نبود). شروع هرچه زودتر پس از تماس یا تشخیص.","Plague approval is based on animal studies (human trials not feasible). Start as soon as possible after exposure or diagnosis.",[85],{"source":34,"section":86},"1.5",[88,97],{"id":89,"severity":90,"text":91,"refs":94},"hyper","block",{"fa":92,"en":93},"حساسیت به موکسی‌فلوکساسین یا هر کینولون.","Hypersensitivity to moxifloxacin or any quinolone.",[95],{"source":34,"section":96},"4",{"id":98,"severity":90,"rule":99,"text":101,"refs":104},"child",{"maxAge":100},{"value":45,"unit":46},{"fa":102,"en":103},"زیر ۱۸ سال اثربخشی ثابت نشده.","Effectiveness under 18 not established.",[105],{"source":34,"section":106},"8.4",[108],{"text":109,"refs":112},{"fa":110,"en":111},"هشدار جعبه‌ای فلوروکینولون‌ها: پارگی تاندون، نوروپاتی محیطی، اثرات CNS، تشدید میاستنی؛ برای سینوزیت و برونشیت فقط اگر گزینه دیگری نیست.","Fluoroquinolone boxed warning: tendon rupture, peripheral neuropathy, CNS effects, myasthenia exacerbation; for sinusitis\u002Fbronchitis only if no alternative.",[113],{"source":34,"section":114},"Boxed Warning",[],[],[118],{"with":119,"text":120,"refs":123},"cations",{"fa":121,"en":122},"۴ ساعت قبل یا ۸ ساعت بعد از منیزیم، آلومینیوم، آهن، روی، آنتی‌اسید و مولتی‌ویتامین.","Take 4 h before or 8 h after magnesium, aluminium, iron, zinc, antacids or multivitamins.",[124],{"source":34,"section":125},"2.2",{"status":127,"reviewer":128,"date":128},"unverified",null,[130,135,138],{"regimen":38,"formulation":23,"input":131,"expect":134},{"ageYears":132,"weightKg":133},40,70,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":56,"formulation":23,"input":136,"expect":137},{"ageYears":132,"weightKg":133},{"perDose":28},{"regimen":69,"formulation":23,"input":139,"expect":140},{"ageYears":132,"weightKg":133},{"perDose":28,"tabletsPerDoseRounded":5},[142],"J01MA14",{"status":144,"forms":145,"refs":158},"registered",[146,150,154],{"code":147,"en":148,"fa":149},"14266","MOXIFLOXACIN 0.5% 5ML OPH DROP","قطره چشمی موکسی‌فلوکساسین ۰٫۵ درصد ۵ میلی‌لیتر",{"code":151,"en":152,"fa":153},"08277","MOXIFLOXACIN HCL 400MG TAB","قرص موکسی‌فلوکساسین هیدروکلراید ۴۰۰ میلی‌گرم",{"code":155,"en":156,"fa":157},"52529","MOXIFLOXACIN SOLUTION, DROPS OPHTHALMIC 0.5 % 0.5 mL","قطره چشمی موکسی‌فلوکساسین ۰٫۵ درصد ۰٫۵ میلی‌لیتر",[159],{"source":160,"section":161,"url":162},"darooyab-generic","G-444\u002FMoxifloxacin","https:\u002F\u002Fwww.darooyab.ir\u002FG-444\u002FMoxifloxacin",[164,168,172,175,178,181],{"kind":165,"url":166,"label":167},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=202632","ANDA202632",{"kind":169,"url":170,"label":171},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f34c08e6-fe74-4de3-9e36-a82c3c1c183b","FDA Moxifloxacin",{"kind":173,"url":174,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa600002.html",{"kind":173,"url":176,"label":177},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa608030.html","Moxifloxacin Injection",{"kind":179,"url":180,"label":142},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01MA14",{"kind":182,"url":162,"label":8},"darooyab",{"pregnancy":184,"lactation":193,"pediatric":202,"geriatric":210},{"level":185,"text":186,"quote":189,"refs":190},"avoid",{"fa":187,"en":188},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Based on animal studies with moxifloxacin, moxifloxacin hydrochloride may cause fetal harm.",[191],{"source":34,"section":192},"8.1",{"level":194,"text":195,"quote":198,"refs":199},"caution",{"fa":196,"en":197},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary It is not known if moxifloxacin is present in human milk.",[200],{"source":34,"section":201},"8.2",{"level":203,"text":204,"quote":207,"refs":208},"not-established",{"fa":205,"en":206},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Effectiveness in pediatric patients and adolescents less than 18 years of age has not been established.",[209],{"source":34,"section":106},{"level":194,"text":211,"quote":214,"refs":215},{"fa":212,"en":213},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Caution should be used when prescribing moxifloxacin hydrochloride to elderly patients especially those on corticosteroids.",[216],{"source":34,"section":217},"8.5",{"kind":219,"refs":220,"id":167},"ANDA",[221],{"source":34,"section":222},"SPL approval \u002F marketing category",1792191874195]