Pegfilgrastim

پگ‌فیلگراستیم

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsLong-acting granulocyte colony-stimulating factor

Market / country: 🇺🇸 USA

Neulasta (US)

🧮 Dose calculator

Febrile neutropenia (empiric therapy) · Regimen source: FDA Neulasta · 2.1

  • • Once per chemotherapy cycle; not between 14 days before and 24 hours after chemotherapy. FDA Neulasta · 2.1
  • • Haematopoietic acute radiation syndrome: two 6 mg doses one week apart. FDA Neulasta · 2.2

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🛡️ Safety & information

Contraindications

  • ⛔ History of serious hypersensitivity to pegfilgrastim or filgrastim. FDA Neulasta · 4

Warnings

  • • Splenic rupture; ARDS; serious hypersensitivity; sickle-cell crises; glomerulonephritis; leukocytosis; capillary leak syndrome; MDS/AML. FDA Neulasta · 5

Formulations

  • 6 mg/0.6 mL prefilled syringe (10 mg/mL) — injection 🇺🇸 USA FDA Neulasta · 3

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Neulasta · 8.1

    “Risk Summary Although available data with Neulasta use in pregnant women are insufficient to establish whether there is a drug associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes, there are available data from published studies in pregnant women exposed to filgrastim products.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Neulasta · 8.2

    “Risk Summary There are no data on the presence of pegfilgrastim in human milk, the effects on the breastfed child, or the effects on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Neulasta · 8.4

    “The safety and effectiveness of Neulasta for chemotherapy-induced neutropenia and hematopoietic subsyndrome of acute radiation syndrome have been established in pediatric patients.”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Neulasta · 8.5

    “No overall differences in safety or effectiveness were observed between patients aged 65 and older and younger patients.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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