Penicillin G benzathine
پنیسیلین بنزاتین
🦠 Antiinfectives For Systemic UseLong-acting penicillin (IM)
Market / country: 🇺🇸 USA
Bicillin L-A (US)
🧮 Dose calculator
Streptococcal pharyngitis / tonsillitis · Regimen source: FDA Bicillin L-A · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ History of hypersensitivity to any penicillin. FDA Bicillin L-A · Contraindications
- ⚠️ Boxed warning: IM only; IV injection has caused cardiorespiratory arrest and death. FDA Bicillin L-A · Boxed Warning
Formulations
- 600,000 units / 1 mL prefilled syringe (600,000 units/mL) — injection 🇺🇸 USA FDA Bicillin L-A · How Supplied
- 1,200,000 units / 2 mL prefilled syringe (600,000 units/mL) — injection 🇺🇸 USA FDA Bicillin L-A · How Supplied
- 2,400,000 units / 4 mL prefilled syringe (600,000 units/mL) — injection 🇺🇸 USA FDA Bicillin L-A · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Bicillin L-A · Pregnancy
“Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Bicillin L-A · Nursing Mothers
“Caution should be exercised when penicillin G benzathine is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Bicillin L-A · Pediatric Use
“(See INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION sections.)”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bicillin L-A · Geriatric Use
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA050141
- DailyMed (FDA label)FDA Bicillin L-A
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDJ01CE08
- Darooyab (Iran)Benzathine-Penicillin
🇮🇷 Registered in Iran Darooyab · G-296/Benzathine-Penicillin
Dosage forms with Iranian generic codes, per Darooyab.
- 01628 · PENICILLIN G BENZATHINE (PEN L A) 600,000 U VIAL · قلم تزریقی پنیسیلین گرم بنزاتین (لیتر A) ۶۰۰۰۰۰ واحد
- 00958 · PENICILLIN G BENZATHINE (PEN LA) 1,200,000 U VIAL · قلم تزریقی پنیسیلین گرم بنزاتین (طولانیاثر) ۱۲۰۰۰۰۰ واحد
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Bicillin L-A · How SuppliedFDA Bicillin L-A · Dosage and AdministrationFDA Bicillin L-A · ContraindicationsFDA Bicillin L-A · Boxed WarningFDA Bicillin L-A · PregnancyFDA Bicillin L-A · Nursing MothersFDA Bicillin L-A · Pediatric UseFDA Bicillin L-A · Geriatric UseFDA Bicillin L-A · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-296/Benzathine-Penicillin
- Clinical review⚠ Unverified