Propylthiouracil (PTU)

🧮 Dose calculator

Hyperthyroidism · Regimen source: FDA Propylthiouracil · Dosage and Administration, Adults

• • Every 8 hours. Severe or large goitre: 400 mg/day (occasionally 600–900). Maintenance 100–150 mg/day. May be preferred in the first trimester of pregnancy. FDA Propylthiouracil · Dosage and Administration, AdultsFDA Propylthiouracil · Dosage and AdministrationFDA Propylthiouracil · Indications and Usage

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Propylthiouracil · Pregnancy

  “Pregnancy Category D.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Propylthiouracil · Nursing Mothers

  “Propylthiouracil is present in breast milk to a small extent and therefore likely results in clinically insignificant doses to the nursing infant.”

• 👶 ChildrenDangerous / avoid

  Boxed warning in the label about children. FDA Propylthiouracil · Boxed Warning

  “These reports of hepatic reactions include cases requiring liver transplantation in adult and pediatric patients.”

• 👴 Older adultsNo data

  The source for this drug has no section for this group.

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.