Tiotropium
تیوتروپیوم (اسپیریوا)
🌬️ Respiratory SystemLong-acting anticholinergic (LAMA)
Market / country: 🇺🇸 USA
Spiriva Respimat (US)
🧮 Dose calculator
Chronic obstructive pulmonary disease (COPD) · Regimen source: FDA Spiriva Respimat · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to tiotropium, ipratropium or any component. FDA Spiriva Respimat · 4
Formulations
- 1.25 mcg per actuation (Respimat) — inhaler 🇺🇸 USA FDA Spiriva Respimat · 3
- 2.5 mcg per actuation (Respimat) — inhaler 🇺🇸 USA FDA Spiriva Respimat · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Spiriva Respimat · 8.1
“Risk Summary The limited human data with SPIRIVA RESPIMAT use during pregnancy are insufficient to inform a drug-associated risk of adverse pregnancy-related outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Spiriva Respimat · 8.2
“Risk Summary There are no data on the presence of tiotropium in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Spiriva Respimat · 8.4
“The safety and efficacy of SPIRIVA RESPIMAT 2.5 mcg have been established in pediatric patients aged 6 to 17 years with asthma in 6 clinical trials up to 1 year in duration.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Spiriva Respimat · 8.5
“Based on available data, no adjustment of SPIRIVA RESPIMAT dosage in geriatric patients is warranted [see Clinical Pharmacology (12.3) ].”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA207070
- DailyMed (FDA label)FDA Spiriva Respimat
- MedlinePlus (NIH)Tiotropium Oral Inhalation
- WHO ATC/DDDR03BB04
- Darooyab (Iran)Tiotropium
🇮🇷 Registered in Iran Darooyab · G-1497/Tiotropium
Dosage forms with Iranian generic codes, per Darooyab.
- 06054 · TIOTROPIUM 18MCG TAB · قرص تیوتروپیوم ۱۸ میکروگرم
- 04189 · TIOTROPIUM 0.018MG FOR INHAL · تیوتروپیوم ۰٫۰۱۸ میلیگرم استنشاقی
- 52358 · TIOTROPIUM (AS BROMIDE) SOLUTION RESPIRATORY 2.5 ug/1{Puff} 30 {dose} · فرآورده استنشاقی تیوتروپیوم (معادل بروماید) ۲٫۵ میکروگرم / ۱ { } ۳۰ { دوز }
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Spiriva Respimat · 3FDA Spiriva Respimat · 2.1FDA Spiriva Respimat · 2.2FDA Spiriva Respimat · 4FDA Spiriva Respimat · 8.1FDA Spiriva Respimat · 8.2FDA Spiriva Respimat · 8.4FDA Spiriva Respimat · 8.5FDA Spiriva Respimat · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1497/Tiotropium
- Clinical review⚠ Unverified