[{"data":1,"prerenderedAt":211},["ShallowReactive",2],{"drug-tobramycin-eye":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":23,"regimens":36,"contraindications":60,"warnings":80,"renal":81,"monitoring":82,"interactions":83,"review":84,"examples":87,"atc":99,"iran":101,"links":157,"populations":172,"usApproval":206},"tobramycin-eye",1,{"fa":7,"en":8},"قطره چشمی توبرامایسین","Tobramycin eye drops","sensory-organs",{"fa":11,"en":12},"آنتی‌بیوتیک آمینوگلیکوزید موضعی چشم","Topical ophthalmic aminoglycoside",[14],{"name":15,"market":16},"Tobrex","US",[18,19,20,21,22],"tobrex","توبرکس","توبرامایسین","قطره چشم","عفونت چشم",[24],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":31,"refs":32},"sol-0-3","eye-drops","ophthalmic","0.3% (3 mg\u002FmL) eye drops",{"amount":5,"unit":30,"perUnit":30},"drop",[16],[33],{"source":34,"section":35},"fda-tobramycin-eye","How Supplied",[37],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":50,"notes":53},"mild","bacterial-conjunctivitis",{"fa":41,"en":42},"عفونت خفیف تا متوسط چشم: ۱ تا ۲ قطره هر ۴ ساعت","Mild–moderate eye infection: 1–2 drops every 4 hours",{"minAge":44},{"value":45,"unit":46},2,"month","fixed",{"perDose":5,"perDoseMax":45,"dosesPerDay":49},6,[51],{"source":34,"section":52},"Dosage and Administration",[54],{"text":55,"refs":58},{"fa":56,"en":57},"عفونت شدید: ۲ قطره هر ساعت تا بهبود، سپس کاهش تدریجی پیش از قطع.","Severe infection: 2 drops hourly until improvement, then reduce before stopping.",[59],{"source":34,"section":52},[61,70],{"id":62,"severity":63,"text":64,"refs":67},"hyper","block",{"fa":65,"en":66},"حساسیت به هر یک از اجزا.","Hypersensitivity to any component.",[68],{"source":34,"section":69},"Contraindications",{"id":71,"severity":63,"rule":72,"text":74,"refs":77},"under-2m",{"maxAge":73},{"value":45,"unit":46},{"fa":75,"en":76},"بی‌خطری و اثربخشی زیر ۲ ماه ثابت نشده.","Safety and effectiveness below 2 months not established.",[78],{"source":34,"section":79},"Pediatric Use",[],[],[],[],{"status":85,"reviewer":86,"date":86},"unverified",null,[88,93],{"regimen":38,"formulation":25,"input":89,"expect":92},{"ageYears":90,"weightKg":91},5,18,{"perDose":5,"upperPerDose":45},{"regimen":38,"formulation":25,"input":94,"expect":97},{"ageYears":95,"weightKg":96},0.1,4,{"status":98},"blocked",[100],"S01AA12",{"status":102,"forms":103,"refs":152},"registered",[104,108,112,116,120,124,128,132,136,140,144,148],{"code":105,"en":106,"fa":107},"18882","TOBRAMYCIN 0.3% OPH OINT","پماد توبرامایسین ۰٫۳ درصد",{"code":109,"en":110,"fa":111},"13022","TOBRAMYCIN 100MG\u002F2ML  INJ","فرآورده تزریقی توبرامایسین ۱۰۰ میلی‌گرم \u002F ۲ میلی‌لیتر",{"code":113,"en":114,"fa":115},"02189","TOBRAMYCIN 10MG\u002FML 2ML AMP","آمپول توبرامایسین ۱۰ میلی‌گرم \u002F میلی‌لیتر ۲ میلی‌لیتر",{"code":117,"en":118,"fa":119},"21537","TOBRAMYCIN 28MG INHALER","فرآورده استنشاقی توبرامایسین ۲۸ میلی‌گرم",{"code":121,"en":122,"fa":123},"16775","TOBRAMYCIN 300MG\u002F4ML NEBULISATION SOLUTION","محلول توبرامایسین ۳۰۰ میلی‌گرم \u002F ۴ میلی‌لیتر نبولایزیشن",{"code":125,"en":126,"fa":127},"11619","TOBRAMYCIN 300MG\u002F5ML AMP","آمپول توبرامایسین ۳۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":129,"en":130,"fa":131},"19893","TOBRAMYCIN 300MG\u002F5ML NEBULISATION","توبرامایسین ۳۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر نبولایزیشن",{"code":133,"en":134,"fa":135},"12781","TOBRAMYCIN 40MG\u002F1ML  INJ","فرآورده تزریقی توبرامایسین ۴۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":137,"en":138,"fa":139},"01229","TOBRAMYCIN 40MG\u002FML 2ML AMP","آمپول توبرامایسین ۴۰ میلی‌گرم \u002F میلی‌لیتر ۲ میلی‌لیتر",{"code":141,"en":142,"fa":143},"06668","TOBRAMYCIN 75MG\u002F1.5ML AMP","آمپول توبرامایسین ۷۵ میلی‌گرم \u002F ۱٫۵ میلی‌لیتر",{"code":145,"en":146,"fa":147},"12805","TOBRAMYCIN 80MG\u002FML 2ML AMP","آمپول توبرامایسین ۸۰ میلی‌گرم \u002F میلی‌لیتر ۲ میلی‌لیتر",{"code":149,"en":150,"fa":151},"51698","TOBRAMYCIN SOLUTION RESPIRATORY 60 mg\u002F1mL 5 mL","محلول توبرامایسین ۶۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۵ میلی‌لیتر",[153],{"source":154,"section":155,"url":156},"darooyab-generic","G-557\u002FTobramycin","https:\u002F\u002Fwww.darooyab.ir\u002FG-557\u002FTobramycin",[158,162,166,169],{"kind":159,"url":160,"label":161},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=211847","ANDA211847",{"kind":163,"url":164,"label":165},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=14c14f81-6b0a-4176-a5df-d0757cc3260d","FDA Tobramycin eye",{"kind":167,"url":168,"label":100},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S01AA12",{"kind":170,"url":156,"label":171},"darooyab","Tobramycin",{"pregnancy":173,"lactation":182,"pediatric":190,"geriatric":197},{"level":174,"text":175,"quote":178,"refs":179},"caution",{"fa":176,"en":177},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.",[180],{"source":34,"section":181},"Pregnancy",{"level":174,"text":183,"quote":186,"refs":187},{"fa":184,"en":185},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Because of the potential for adverse reactions in nursing infants from tobramycin ophthalmic solution, a decision should be made whether to discontinue nursing the infant or discontinue the drug, taking into account the importance of the drug to the mother.",[188],{"source":34,"section":189},"Nursing Mothers",{"level":174,"text":191,"quote":194,"refs":195},{"fa":192,"en":193},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness in pediatric patients below the age of 2 months has not been established.",[196],{"source":34,"section":79},{"level":198,"text":199,"quote":202,"refs":203},"ok",{"fa":200,"en":201},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness have been observed between elderly and younger patients.",[204],{"source":34,"section":205},"Geriatric Use",{"kind":207,"refs":208,"id":161},"ANDA",[209],{"source":34,"section":210},"SPL approval \u002F marketing category",1792191881852]