[{"data":1,"prerenderedAt":172},["ShallowReactive",2],{"drug-tolterodine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":42,"contraindications":65,"warnings":75,"renal":76,"monitoring":77,"interactions":78,"review":79,"examples":82,"atc":89,"iran":91,"links":115,"populations":132,"usApproval":167},"tolterodine",1,{"fa":7,"en":8},"تولترودین","Tolterodine","genitourinary-sex-hormones",{"fa":11,"en":12},"آنتی‌موسکارینی ادراری","Urinary antimuscarinic",[14],{"name":15,"market":16},"Detrol","US",[18,19,7],"detrol","دترول",[21,34],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":29,"refs":30},"tab-1","tablet","oral","1 mg tablet",{"amount":5,"unit":27,"perUnit":23,"scored":28},"mg",false,[16],[31],{"source":32,"section":33},"fda-tolterodine","How Supplied",{"id":35,"form":23,"route":24,"label":36,"concentration":37,"markets":39,"refs":40},"tab-2","2 mg tablet",{"amount":38,"unit":27,"perUnit":23,"scored":28},2,[16],[41],{"source":32,"section":33},[43],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":55,"notes":58},"oab","overactive-bladder",{"fa":47,"en":48},"مثانه بیش‌فعال — ۲ mg دو بار در روز","Overactive bladder — 2 mg twice daily",{"minAge":50},{"value":51,"unit":52},18,"year","fixed",{"perDose":38,"dosesPerDay":38},[56],{"source":32,"section":57},"Dosage and Administration",[59],{"text":60,"refs":63},{"fa":61,"en":62},"بر اساس پاسخ می‌توان ۱ mg دو بار داد؛ نارسایی کبد\u002Fکلیه یا مهارکننده قوی CYP3A4: ۱ mg دو بار.","May lower to 1 mg twice daily; hepatic\u002Frenal impairment or strong CYP3A4 inhibitors: 1 mg twice daily.",[64],{"source":32,"section":57},[66],{"id":67,"severity":68,"text":69,"refs":72},"ci","block",{"fa":70,"en":71},"احتباس ادرار یا معده؛ گلوکوم زاویه بسته کنترل‌نشده؛ حساسیت به تولترودین یا فزوترودین.","Urinary or gastric retention; uncontrolled narrow-angle glaucoma; hypersensitivity to tolterodine or fesoterodine.",[73],{"source":32,"section":74},"Contraindications",[],[],[],[],{"status":80,"reviewer":81,"date":81},"unverified",null,[83],{"regimen":44,"formulation":35,"input":84,"expect":87},{"ageYears":85,"weightKg":86},60,70,{"perDose":38,"perDay":88},4,[90],"G04BD07",{"status":92,"forms":93,"refs":110},"registered",[94,98,102,106],{"code":95,"en":96,"fa":97},"04578","TOLTERODINE 1MG TAB","قرص تولترودین ۱ میلی‌گرم",{"code":99,"en":100,"fa":101},"21323","TOLTERODINE 2MG EXTENDED RELEASE CAP","کپسول آهسته‌رهش تولترودین ۲ میلی‌گرم",{"code":103,"en":104,"fa":105},"04579","TOLTERODINE 2MG TAB","قرص تولترودین ۲ میلی‌گرم",{"code":107,"en":108,"fa":109},"07115","TOLTERODINE 4MG EXTENDED RELEASE CAP","کپسول آهسته‌رهش تولترودین ۴ میلی‌گرم",[111],{"source":112,"section":113,"url":114},"darooyab-generic","G-927\u002FTolterodine","https:\u002F\u002Fwww.darooyab.ir\u002FG-927\u002FTolterodine",[116,120,124,127,130],{"kind":117,"url":118,"label":119},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=204721","ANDA204721",{"kind":121,"url":122,"label":123},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=b9ba8ad2-27f6-4f18-bd84-73659047910e","FDA Tolterodine",{"kind":125,"url":126,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa699026.html",{"kind":128,"url":129,"label":90},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G04BD07",{"kind":131,"url":114,"label":8},"darooyab",{"pregnancy":133,"lactation":142,"pediatric":150,"geriatric":158},{"level":134,"text":135,"quote":138,"refs":139},"caution",{"fa":136,"en":137},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Pregnancy Category C.",[140],{"source":32,"section":141},"Pregnancy",{"level":134,"text":143,"quote":146,"refs":147},{"fa":144,"en":145},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Tolterodine is excreted into the milk in mice.",[148],{"source":32,"section":149},"Nursing Mothers",{"level":134,"text":151,"quote":154,"refs":155},{"fa":152,"en":153},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Efficacy in the pediatric population has not been demonstrated.",[156],{"source":32,"section":157},"Pediatric Use",{"level":159,"text":160,"quote":163,"refs":164},"ok",{"fa":161,"en":162},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety were observed between the older and younger patients (see CLINICAL PHARMACOLOGY, Pharmacokinetics in Special Populations ).",[165],{"source":32,"section":166},"Geriatric Use",{"kind":168,"refs":169,"id":119},"ANDA",[170],{"source":32,"section":171},"SPL approval \u002F marketing category",1792191871539]