Tramadol
ترامادول
🧠 Nervous SystemOpioid analgesic
Market / country: 🇺🇸 USA
Ultram (US)
🧮 Dose calculator
Mild to moderate pain · Regimen source: FDA Tramadol · 2
- • Start 25 mg/day, increase by 25 mg every 3 days to 100 mg/day (25 four times daily), then by 50 mg every 3 days to 200 mg/day. Over 75 y max 300 mg/day. Severe renal impairment: 12-hour interval. FDA Tramadol · 2FDA Tramadol · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Contraindicated under 12 years (fatal respiratory depression). FDA Tramadol · 4
- ⛔ After tonsillectomy/adenoidectomy under 18; respiratory depression; acute or severe asthma unmonitored; GI obstruction; opioid hypersensitivity; MAOI within 14 days. FDA Tramadol · 4
- ⚠️ Boxed warning: addiction and misuse, respiratory depression, fatal accidental ingestion by children, interaction with benzodiazepines. FDA Tramadol · Boxed Warning
Formulations
- 25 mg tablet — tablet 🇺🇸 USA FDA Tramadol · 3
- 50 mg tablet (scored) — tablet 🇺🇸 USA FDA Tramadol · 3
- 75 mg tablet (scored) — tablet 🇺🇸 USA FDA Tramadol · 3
- 100 mg tablet (scored) — tablet 🇺🇸 USA FDA Tramadol · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Tramadol · Boxed Warning
“Neonatal Opioid Withdrawal Syndrome (NOWS) Advise pregnant women using opioids for an extended period of time of the risk of Neonatal Opioid Withdrawal Syndrome, which may be life-threatening if not recognized and treated.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Tramadol · 8.2
“Because of the potential for serious adverse reactions, including excess sedation and respiratory depression in a breastfed infant, advise patients that breastfeeding is not recommended during treatment with tramadol hydrochloride tablets [see Warnings and Precautions (5.4) ] .”
- 👶 ChildrenContraindicated
Label: contraindicated in children below a stated age. FDA Tramadol · 4
“Tramadol Hydrochloride Tablets, USP are contraindicated for: • all children younger than 12 years of age [see Warnings and Precautions (5.4) ]. • post-operative management in children younger than 18 years of age following tonsillectomy and/or adenoidectomy [see Warnings and Precautions (5.4) ].”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tramadol · 8.5
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to to regularly evaluate renal function.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Tramadol · 8.3
“Infertility Use of opioids for an extended period of time may cause reduced fertility in females and males of reproductive potential.”
🔗 Reference links
- FDA (approval record)ANDA208708
- DailyMed (FDA label)FDA Tramadol
- MedlinePlus (NIH)Tramadol
- WHO ATC/DDDN02AX02
- Darooyab (Iran)Tramadol
🇮🇷 Registered in Iran Darooyab · G-205/Tramadol
Dosage forms with Iranian generic codes, per Darooyab.
- 11402 · TRAMADOL 100MG SUSP · سوسپانسیون ترامادول ۱۰۰ میلیگرم
- 08921 · TRAMADOL 10ML DROP · قطره ترامادول ۱۰ میلیلیتر
- 02103 · TRAMADOL HCL 100MG TAB · قرص ترامادول هیدروکلراید ۱۰۰ میلیگرم
- 02013 · TRAMADOL HCL 100MG/2ML AMP · آمپول ترامادول هیدروکلراید ۱۰۰ میلیگرم / ۲ میلیلیتر
- 06491 · TRAMADOL HCL 20MG CAP · کپسول ترامادول هیدروکلراید ۲۰ میلیگرم
- 01982 · TRAMADOL HCL 50MG CAP · کپسول ترامادول هیدروکلراید ۵۰ میلیگرم
- 02102 · TRAMADOL HCL 50MG TAB · قرص ترامادول هیدروکلراید ۵۰ میلیگرم
- 02708 · TRAMADOL HCL 50MG/1ML AMP · آمپول ترامادول هیدروکلراید ۵۰ میلیگرم / ۱ میلیلیتر
- 02190 · TRAMADOL HCL SR 100MG TAB · قرص آهستهرهش ترامادول هیدروکلراید ۱۰۰ میلیگرم
- 11401 · TRAMADOL HYDROCHLORIDE SR 200MG TAB · قرص آهستهرهش ترامادول هیدروکلراید ۲۰۰ میلیگرم
- 52843 · TRAMADOL HYDROCHLORIDE TABLET, EXTENDED RELEASE ORAL 200 mg · قرص آهستهرهش ترامادول هیدروکلراید ۲۰۰ میلیگرم
- 52898 · TRAMADOL HYDROCHLORIDE TABLET, EXTENDED RELEASE ORAL 300 mg · قرص آهستهرهش ترامادول هیدروکلراید ۳۰۰ میلیگرم
- 53076 · TRAMADOL HYDROCHLORIDE INJECTION PARENTERAL 50 mg/1mL 2 mL · فرآورده تزریقی ترامادول هیدروکلراید ۵۰ میلیگرم / ۱ میلیلیتر ۲ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Tramadol · 3FDA Tramadol · 2FDA Tramadol · 2.3FDA Tramadol · 4FDA Tramadol · Boxed WarningFDA Tramadol · 8.2FDA Tramadol · 8.5FDA Tramadol · 8.3FDA Tramadol · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-205/Tramadol
- Clinical review⚠ Unverified