Tramadol

ترامادول

⚠ Unverified

🧠 Nervous SystemOpioid analgesic

Market / country: 🇺🇸 USA

Ultram (US)

🧮 Dose calculator

Mild to moderate pain · Regimen source: FDA Tramadol · 2

  • • Start 25 mg/day, increase by 25 mg every 3 days to 100 mg/day (25 four times daily), then by 50 mg every 3 days to 200 mg/day. Over 75 y max 300 mg/day. Severe renal impairment: 12-hour interval. FDA Tramadol · 2FDA Tramadol · 2.3

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Contraindicated under 12 years (fatal respiratory depression). FDA Tramadol · 4
  • ⛔ After tonsillectomy/adenoidectomy under 18; respiratory depression; acute or severe asthma unmonitored; GI obstruction; opioid hypersensitivity; MAOI within 14 days. FDA Tramadol · 4
  • ⚠️ Boxed warning: addiction and misuse, respiratory depression, fatal accidental ingestion by children, interaction with benzodiazepines. FDA Tramadol · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Tramadol · Boxed Warning

    “Neonatal Opioid Withdrawal Syndrome (NOWS) Advise pregnant women using opioids for an extended period of time of the risk of Neonatal Opioid Withdrawal Syndrome, which may be life-threatening if not recognized and treated.”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Tramadol · 8.2

    “Because of the potential for serious adverse reactions, including excess sedation and respiratory depression in a breastfed infant, advise patients that breastfeeding is not recommended during treatment with tramadol hydrochloride tablets [see Warnings and Precautions (5.4) ] .”
  • 👶 ChildrenContraindicated

    Label: contraindicated in children below a stated age. FDA Tramadol · 4

    “Tramadol Hydrochloride Tablets, USP are contraindicated for: • all children younger than 12 years of age [see Warnings and Precautions (5.4) ]. • post-operative management in children younger than 18 years of age following tonsillectomy and/or adenoidectomy [see Warnings and Precautions (5.4) ].”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tramadol · 8.5

    “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to to regularly evaluate renal function.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Tramadol · 8.3

    “Infertility Use of opioids for an extended period of time may cause reduced fertility in females and males of reproductive potential.”

📚 Reference status for this drug

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