[{"data":1,"prerenderedAt":177},["ShallowReactive",2],{"drug-tranexamic-acid":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":37,"contraindications":65,"warnings":75,"renal":76,"monitoring":77,"interactions":78,"review":79,"examples":82,"atc":89,"iran":91,"links":119,"populations":138,"usApproval":172},"tranexamic-acid",1,{"fa":7,"en":8},"ترانگزامیک اسید","Tranexamic acid","blood",{"fa":11,"en":12},"ضدفیبرینولیز","Antifibrinolytic",[14],{"name":15,"market":16},"Lysteda","US",[18,19,7,20,21],"lysteda","ترانکسامیک","خونریزی قاعدگی","TXA",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":32,"refs":33},"tab-650","tablet","oral","650 mg tablet",{"amount":29,"unit":30,"perUnit":25,"scored":31},650,"mg",false,[16],[34],{"source":35,"section":36},"fda-tranexamic","3",[38],{"id":39,"disease":40,"label":41,"population":44,"type":48,"unit":30,"dose":49,"refs":52,"durationDays":55,"notes":57},"hmb","heavy-menstrual-bleeding",{"fa":42,"en":43},"خونریزی شدید قاعدگی — ۱۳۰۰ mg سه بار در روز، حداکثر ۵ روز","Heavy menstrual bleeding — 1,300 mg three times daily, max 5 days",{"minAge":45},{"value":46,"unit":47},12,"year","fixed",{"perDose":50,"dosesPerDay":51},1300,3,[53],{"source":35,"section":54},"2.2",{"min":5,"max":56},5,[58],{"text":59,"refs":62},{"fa":60,"en":61},"فقط در روزهای قاعدگی. کراتینین بالای ۱٫۴ mg\u002FdL: دوز کمتر.","During menstruation only. Creatinine above 1.4 mg\u002FdL: lower dose.",[63],{"source":35,"section":64},"2",[66],{"id":67,"severity":68,"text":69,"refs":72},"ci","block",{"fa":70,"en":71},"همراه قرص‌های ترکیبی هورمونی؛ ترومبوآمبولی فعال یا سابقه یا خطر ذاتی ترومبوز؛ حساسیت.","With combined hormonal contraceptives; active, past or intrinsic risk of thromboembolism; hypersensitivity.",[73],{"source":35,"section":74},"4",[],[],[],[],{"status":80,"reviewer":81,"date":81},"unverified",null,[83],{"regimen":39,"formulation":24,"input":84,"expect":87},{"ageYears":85,"weightKg":86},30,60,{"perDose":50,"tabletsPerDoseRounded":88},2,[90],"B02AA02",{"status":92,"forms":93,"refs":114},"registered",[94,98,102,106,110],{"code":95,"en":96,"fa":97},"02105","TRANEXAMIC ACID 100MG\u002FML 10ML AMP","آمپول ترانگزامیک اسید ۱۰۰ میلی‌گرم \u002F میلی‌لیتر ۱۰ میلی‌لیتر",{"code":99,"en":100,"fa":101},"01239","TRANEXAMIC ACID 250 CAP","کپسول ترانگزامیک اسید ۲۵۰",{"code":103,"en":104,"fa":105},"02106","TRANEXAMIC ACID 500MG TAB","قرص ترانگزامیک اسید ۵۰۰ میلی‌گرم",{"code":107,"en":108,"fa":109},"01238","TRANEXAMIC ACID 500MG\u002F5ML AMP","آمپول ترانگزامیک اسید ۵۰۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":111,"en":112,"fa":113},"01240","TRANEXAMIC ACID 50MG\u002FML 5ML AMP","آمپول ترانگزامیک اسید ۵۰ میلی‌گرم \u002F میلی‌لیتر ۵ میلی‌لیتر",[115],{"source":116,"section":117,"url":118},"darooyab-generic","G-1426\u002FTranexamic-Acid","https:\u002F\u002Fwww.darooyab.ir\u002FG-1426\u002FTranexamic-Acid",[120,124,128,132,135],{"kind":121,"url":122,"label":123},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=205133","ANDA205133",{"kind":125,"url":126,"label":127},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=4877eacd-fda7-4708-93a5-81052c1d2e14","FDA Tranexamic acid",{"kind":129,"url":130,"label":131},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa612021.html","Tranexamic Acid",{"kind":133,"url":134,"label":90},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=B02AA02",{"kind":136,"url":118,"label":137},"darooyab","Tranexamic-Acid",{"pregnancy":139,"lactation":148,"pediatric":156,"geriatric":164},{"level":140,"text":141,"quote":144,"refs":145},"caution",{"fa":142,"en":143},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Tranexamic acid is not indicated for use in pregnant women .",[146],{"source":35,"section":147},"8.1",{"level":140,"text":149,"quote":152,"refs":153},{"fa":150,"en":151},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Tranexamic acid is present in the mother’s milk at a concentration of about one hundredth of the corresponding serum concentration (see Data).",[154],{"source":35,"section":155},"8.2",{"level":140,"text":157,"quote":160,"refs":161},{"fa":158,"en":159},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of tranexamic acid have been established in females of reproductive potential.",[162],{"source":35,"section":163},"8.4",{"level":140,"text":165,"quote":168,"refs":169},{"fa":166,"en":167},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Tranexamic acid is indicated for females of reproductive potential and is not intended for use by postmenopausal women.",[170],{"source":35,"section":171},"8.5",{"kind":173,"refs":174,"id":123},"ANDA",[175],{"source":35,"section":176},"SPL approval \u002F marketing category",1792440722219]