Varenicline

🧮 Dose calculator

Smoking cessation · Regimen source: FDA Varenicline · 2

• • Days 1–3: 0.5 mg once daily; days 4–7: 0.5 mg twice daily; then 1 mg twice daily to 12 weeks. CrCl <30: max 0.5 mg twice daily. FDA Varenicline · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Varenicline · 8.1

  “Risk Summary Available data have not suggested an increased risk for major birth defects following exposure to varenicline in pregnancy, compared with women who smoke [see Data] .”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Varenicline · 8.2

  “Risk Summary There are no data on the presence of varenicline in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Varenicline · 8.4

  “Varenicline tablets is not recommended for use in pediatric patients 16 years of age or younger because its efficacy in this population was not demonstrated.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Varenicline · 8.5

  “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration (2.2) ].”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.