Type 2 diabetes mellitus

Type 2 diabetes mellitus · ICD-10: E11.9

Symptoms

  • • Often no symptoms at first
  • • Increased thirst
  • • Increased urination
  • • Hunger
  • • Fatigue
  • • Blurred vision
  • • Frequent bladder, kidney or skin infections

MedlinePlus · Symptoms

Drugs and regimens

Acarbose⚠ Unverified

Type 2 diabetes — start 25 mg three times daily with the first bite

Canagliflozin⚠ Unverified

Type 2 diabetes (adults and children ≥10 y) — 100 mg once daily before the first meal; up to 300 mg if eGFR ≥60

Dapagliflozin⚠ Unverified

Type 2 diabetes — ≥10 y: 5 mg once daily

Dulaglutide⚠ Unverified

Type 2 diabetes — once weekly: 0.75 mg, then 1.5 mg; max 4.5 mg

Dulaglutide⚠ Unverified

Type 2 diabetes, children ≥10 y — 0.75 mg weekly, max 1.5 mg

Empagliflozin⚠ Unverified

Type 2 diabetes — ≥10 y: 10 mg in the morning

Ertugliflozin⚠ Unverified

Type 2 diabetes, adults — 5 mg in the morning; up to 15 mg once daily

Exenatide⚠ Unverified

Type 2 diabetes — 5 mcg SC twice daily within 60 min before morning and evening meals; 10 mcg after 1 month

Glibenclamide (glyburide)⚠ Unverified

Type 2 diabetes — start 2.5–5 mg with breakfast

Glibenclamide (glyburide)⚠ Unverified

Under 18 years

Gliclazide⚠ Unverified

Type 2 diabetes — 80 mg IR tablet: start 40–80 mg/day

Gliclazide⚠ Unverified

Type 2 diabetes — modified release (MR): start 30 mg at breakfast

Gliclazide⚠ Unverified

Under 18 years

Glimepiride⚠ Unverified

Type 2 diabetes — start 1 or 2 mg with breakfast

Glimepiride⚠ Unverified

Under 18 years

Glipizide⚠ Unverified

Type 2 diabetes — start 5 mg before breakfast

Glipizide⚠ Unverified

Under 18 years

Insulin degludec⚠ Unverified

Type 2 diabetes, insulin-naive — 10 units once daily

Insulin detemir⚠ Unverified

Type 2 diabetes — 10 units (or 0.1–0.2 units/kg) once daily in the evening

Insulin glargine⚠ Unverified

Type 2 diabetes (starting insulin)

Insulin lispro⚠ Unverified

Type 2 diabetes — individualised mealtime dose

Insulin regular (human)⚠ Unverified

Type 2 diabetes

Linagliptin⚠ Unverified

Type 2 diabetes — 5 mg once daily

Liraglutide⚠ Unverified

Type 2 diabetes (≥10 y) — 0.6 mg daily, then 1.2 up to 1.8 mg

Metformin⚠ Unverified

Children ≥10 years — start 500 mg twice daily

Metformin⚠ Unverified

Adults — start 500 mg twice daily

Pioglitazone⚠ Unverified

Type 2 diabetes — start 15 or 30 mg once daily

Pioglitazone⚠ Unverified

Under 18 years

Pramlintide⚠ Unverified

Type 2 diabetes on mealtime insulin — 60 mcg before each major meal; up to 120 mcg

Repaglinide⚠ Unverified

Type 2 diabetes — 0.5 mg before each meal (HbA1c ≥8%: 1–2 mg)

Semaglutide (weekly injection)⚠ Unverified

Type 2 diabetes — once weekly: 0.25 mg × 4 weeks, then 0.5 mg

Sitagliptin⚠ Unverified

Type 2 diabetes — 100 mg once daily

Sitagliptin⚠ Unverified

Under 18 years

Tirzepatide (weekly injection)⚠ Unverified

Type 2 diabetes — once weekly: start 2.5 mg

Vildagliptin⚠ Unverified

Type 2 diabetes — 50 mg twice daily (with a sulphonylurea: 50 mg in the morning)

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