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Allopurinol

آلوپورینول

⚠ Unverified

🦴 Musculo-Skeletal SystemXanthine oxidase inhibitor

🤰 Pregnancy:Dangerous / avoid 🤱 Breastfeeding:Dangerous / avoid 👶 Children:Use with caution 🇮🇷 Registered in Iran ⛔ 1 contraindications 🇺🇸 FDA approved generic (ANDA) ANDA204467 ATC M04AA01

Market / country: 🇺🇸 USA

Zyloprim (US)

🧮 Dose calculator

Disease / regimen

Gout · Regimen source: FDA Allopurinol · 2.3

• Increase by 100 mg weekly until uric acid ≤6 mg/dL; max 800 mg/day. Renal impairment: start 50 mg. Treat flares alongside. FDA Allopurinol · 2.3 FDA Allopurinol · 2

Formulation

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🛡️ Safety & information

Contraindications

⛔ History of hypersensitivity reaction to allopurinol. FDA Allopurinol · 4

Formulations

100 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3
200 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3
300 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3

👥 Special populations

🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Allopurinol · 8.1
“Risk Summary Based on findings in animals, allopurinol tablets may cause fetal harm when administered to a pregnant woman.”
🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Allopurinol · 8.2
“Because of the potential for serious adverse reactions in a breastfed child, advise women not to breastfeed during treatments with allopurinol tablets and for one week after the last dose.”
👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Allopurinol · 8.4
“Hyperuricemia Associated with Cancer Therapy The safety and effectiveness of allopurinol for the management of pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels have been established in approximately …”
👴 Older adultsNo data
The source for this drug has no section for this group.
⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.

🔗 Reference links

FDA (approval record)ANDA204467
DailyMed (FDA label)FDA Allopurinol
MedlinePlus (NIH)Allopurinol Allopurinol Injection
WHO ATC/DDDM04AA01
Darooyab (Iran)Allopurinol

🇮🇷 Registered in Iran Darooyab · G-754/Allopurinol

Dosage forms with Iranian generic codes, per Darooyab.

00038 · ALLOPURINOL 100MG TAB · قرص آلوپورینول ۱۰۰ میلی‌گرم
02017 · ALLOPURINOL 300MG TAB · قرص آلوپورینول ۳۰۰ میلی‌گرم

📚 Reference status for this drug

Shows which sources have references recorded for this drug and which do not.

FDA label (DailyMed)✅ Present
FDA Allopurinol · 3 FDA Allopurinol · 2.3 FDA Allopurinol · 2 FDA Allopurinol · 2.5 FDA Allopurinol · 2.4 FDA Allopurinol · 4 FDA Allopurinol · 8.1 FDA Allopurinol · 8.2 FDA Allopurinol · 8.4 FDA Allopurinol · SPL approval / marketing category
UK SmPC (eMC / MHRA)❌ Not present
Published guideline❌ Not present
Licensed reference (medical school)❌ Not present
Iranian leaflet (IFDA)❌ Not present
Pharmacy website (secondary, unreliable)✅ Present
Darooyab · G-754/Allopurinol
Clinical review⚠ Unverified