Apixaban

🧮 Dose calculator

Atrial fibrillation / anticoagulation · Regimen source: FDA Eliquis · 2.1

• • If at least 2 of age ≥80, weight ≤60 kg, creatinine ≥1.5: 2.5 mg twice daily. Halve with combined strong CYP3A4 + P-gp inhibitors. FDA Eliquis · 2FDA Eliquis · 2.6

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Eliquis · 8.1

  “Risk Summary The limited available data on ELIQUIS use in pregnant women are insufficient to inform drug-associated risks of major birth defects, miscarriage, or adverse developmental outcomes.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Eliquis · 8.2

  “Because human exposure through milk is unknown, breastfeeding is not recommended during treatment with ELIQUIS.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Eliquis · 8.4

  “The safety and effectiveness of ELIQUIS for the treatment of VTE and the reduction in the risk of recurrent VTE have been established in pediatric patients aged birth and older.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Eliquis · 8.5

  “Of the total subjects in the ARISTOTLE and AVERROES clinical studies, >69% were 65 years of age and older, and >31% were 75 years of age and older.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Eliquis · 8.3

  “Females of reproductive potential requiring anticoagulation should discuss pregnancy planning with their physician.”