Carbidopa/levodopa

کاربیدوپا-لوودوپا

⚠ Unverified

🧠 Nervous SystemDopamine precursor

Market / country: 🇺🇸 USA

Sinemet (US)

🧮 Dose calculator

Parkinson's disease · Regimen source: FDA Carbidopa-levodopa · Dosage and Administration, Usual Initial Dosage

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Carbidopa-levodopa · Precautions/Warnings – Pregnancy

    “No teratogenic effects were observed in a study in mice receiving up to 20 times the maximum recommended human dose of carbidopa and levodopa.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Carbidopa-levodopa · Precautions/Warnings – Nursing Mothers

    “Caution should be exercised when carbidopa and levodopa is administered to a nursing woman.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Carbidopa-levodopa · Precautions/Warnings – Pediatric Use

    “Safety and effectiveness in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Carbidopa-levodopa · Precautions/Warnings – Geriatric Use

    “In the clinical efficacy trials for carbidopa and levodopa, almost half of the patients were older than 65, but few were older than 75.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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