Celecoxib

سلکوکسیب

⚠ Unverified

🦴 Musculo-Skeletal SystemCOX-2 selective NSAID

Market / country: 🇺🇸 USA

Celebrex (US)

🧮 Dose calculator

Osteoarthritis · Regimen source: FDA Celecoxib · 2.2

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🛡️ Safety & information

Contraindications

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Celecoxib · 8.1

    “Clinical Considerations Fetal/Neonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including celecoxib, can cause premature closure of the fetal ductus arteriosus (see Data) .”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Celecoxib · 8.2

    “Caution should be exercised when celecoxib is administered to a nursing woman.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Celecoxib · 8.4

    “Celecoxib is approved for relief of the signs and symptoms of Juvenile Rheumatoid Arthritis in patients 2 years and older.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Celecoxib · Boxed Warning

    “Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events [see Warnings and Precautions (5.2) ] .”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Celecoxib · 8.3

    “Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including celecoxib, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.”

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