Celecoxib
سلکوکسیب
🦴 Musculo-Skeletal SystemCOX-2 selective NSAID
Market / country: 🇺🇸 USA
Celebrex (US)
🧮 Dose calculator
Osteoarthritis · Regimen source: FDA Celecoxib · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to celecoxib; CABG surgery (and other items in section 4). FDA Celecoxib · 4FDA Celecoxib · Boxed Warning
- ⚠️ Boxed warning: risk of serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation. FDA Celecoxib · Boxed Warning
Formulations
- 50 mg capsule — capsule 🇺🇸 USA FDA Celecoxib · 3
- 100 mg capsule — capsule 🇺🇸 USA FDA Celecoxib · 3
- 200 mg capsule — capsule 🇺🇸 USA FDA Celecoxib · 3
- 400 mg capsule — capsule 🇺🇸 USA FDA Celecoxib · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Celecoxib · 8.1
“Clinical Considerations Fetal/Neonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including celecoxib, can cause premature closure of the fetal ductus arteriosus (see Data) .”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Celecoxib · 8.2
“Caution should be exercised when celecoxib is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Celecoxib · 8.4
“Celecoxib is approved for relief of the signs and symptoms of Juvenile Rheumatoid Arthritis in patients 2 years and older.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Celecoxib · Boxed Warning
“Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events [see Warnings and Precautions (5.2) ] .”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Celecoxib · 8.3
“Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including celecoxib, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.”
🔗 Reference links
- FDA (approval record)ANDA200562
- DailyMed (FDA label)FDA Celecoxib
- MedlinePlus (NIH)Celecoxib
- WHO ATC/DDDM01AH01
- Darooyab (Iran)Celecoxib
🇮🇷 Registered in Iran Darooyab · G-41/Celecoxib
Dosage forms with Iranian generic codes, per Darooyab.
- 01913 · CELECOXIB 100MG CAP · کپسول سلکوکسیب ۱۰۰ میلیگرم
- 01932 · CELECOXIB 200MG CAP · کپسول سلکوکسیب ۲۰۰ میلیگرم
- 53361 · CELECOXIB 400MG CAP · کپسول سلکوکسیب ۴۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Celecoxib · 3FDA Celecoxib · 2.2FDA Celecoxib · 2.3FDA Celecoxib · 2.5FDA Celecoxib · 2.6FDA Celecoxib · 2.4FDA Celecoxib · 2FDA Celecoxib · 4FDA Celecoxib · Boxed WarningFDA Celecoxib · 8.1FDA Celecoxib · 8.2FDA Celecoxib · 8.4FDA Celecoxib · 8.3FDA Celecoxib · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-41/Celecoxib
- Clinical review⚠ Unverified