Chlorphenamine (chlorpheniramine)
کلرفنیرامین
🌬️ Respiratory SystemFirst-generation antihistamine
Market / country: 🇬🇧 UK
Piriton (GB) · Chlor-Trimeton (US)
🧮 Dose calculator
Allergic conditions (hay fever, urticaria, angioedema, insect bites, chickenpox itch) · Regimen source: UK SmPC Piriton · 4.2UK SmPC Piriton · 4.1
- • Every 4–6 h (1–2 years: twice daily). Daily max: 1–2 y 2 mg; 2–6 y 6 mg; 6–12 y 12 mg; ≥12 y 24 mg. Not continuously >2 weeks without advice. Not recommended under 1 year. UK SmPC Piriton · 4.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Not recommended for children below 1 year. UK SmPC Piriton · 4.2
- ⛔ MAOI treatment within the last 14 days; hypersensitivity to antihistamines. UK SmPC Piriton · 4.3
Warnings
- • Caution in epilepsy, glaucoma, prostatic hypertrophy, asthma/bronchitis, hepatic or renal impairment; paradoxical excitation in children. UK SmPC Piriton · 4.4
Formulations
- 2 mg / 5 mL syrup — syrup 🇬🇧 UK UK SmPC Piriton · 2
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. UK SmPC Piriton · 4.6
“There are no adequate data from the use of chlorphenamine in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. UK SmPC Piriton · 4.6
“Chlorphenamine maleate and other antihistamines may inhibit lactation and may be secreted in breast milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. UK SmPC Piriton · 4.2
“Children aged 6 - 12 years : 5ml (2mg) every 4 to 6 hourly.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. UK SmPC Piriton · 4.2
“Elderly : The elderly are more likely to experience neurological anticholinergic effects.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)❌ None
- DailyMed (FDA label)❌ None
- MedlinePlus (NIH)ChlorpheniramineDextromethorphan
- WHO ATC/DDDR06AB04
- Darooyab (Iran)Chlorpheniramine-Maleate
- eMC (UK label)UK SmPC Piriton
🇮🇷 Registered in Iran Darooyab · G-779/Chlorpheniramine-Maleate
Dosage forms with Iranian generic codes, per Darooyab.
- 00275 · CHLORPHENIRAMINE MALEATE 10MG/1ML AMP · آمپول کلرفنیرامین مالئات ۱۰ میلیگرم / ۱ میلیلیتر
- 02014 · CHLORPHENIRAMINE MALEATE 2MG/5ML 60ML SYRUP · شربت کلرفنیرامین مالئات ۲ میلیگرم / ۵ میلیلیتر ۶۰ میلیلیتر
- 00276 · CHLORPHENIRAMINE MALEATE 4MG TAB · قرص کلرفنیرامین مالئات ۴ میلیگرم
- 01431 · CHLORPHENIRAMINE MALEATE SR 8MG TAB · قرص آهستهرهش کلرفنیرامین مالئات ۸ میلیگرم
- 00402 · DEXCHLORPHENIRAMINE MALEATE 2MG TAB · قرص دکسکلرفنیرامین مالئات ۲ میلیگرم
- 00401 · DEXCHLORPHENIRAMINE MALEATE 2MG/5ML SYRUP · شربت دکسکلرفنیرامین مالئات ۲ میلیگرم / ۵ میلیلیتر
- 01459 · DEXCHLORPHENIRAMINE MALEATE SR 6MG TAB · قرص آهستهرهش دکسکلرفنیرامین مالئات ۶ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)❌ Not present
- UK SmPC (eMC / MHRA)✅ PresentUK SmPC Piriton · 2UK SmPC Piriton · 4.2UK SmPC Piriton · 4.1UK SmPC Piriton · 4.3UK SmPC Piriton · 4.4UK SmPC Piriton · 4.6
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-779/Chlorpheniramine-Maleate
- Clinical review⚠ Unverified