Cyclosporine (oral, modified)

🧮 Dose calculator

Rheumatoid arthritis · Regimen source: FDA Neoral · Dosage and Administration

• • Neoral and Sandimmune are not bioequivalent and must not be interchanged without physician supervision. Always in two doses. Monitor BP and creatinine. FDA Neoral · Dosage and Administration
• • Onset 4–8 weeks. Increase by 0.5–0.75 mg/kg/day after 8 and 12 weeks up to 4 mg/kg/day. FDA Neoral · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Neoral · Pregnancy

  “Risk Summary Available data from published literature, including the Transplant Pregnancy Registry International, observational cohort studies, case-controlled studies, meta-analysis, case series, and case reports, over decades of use with cyclosporine in pregnancy have not identified a drug associated risk of major …”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Neoral · Nursing Mothers

  “Risk Summary Cyclosporine and its metabolites are present in human milk following oral and intravenous administration.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Neoral · Pediatric Use

  “The safety and efficacy of Neoral treatment in children with juvenile rheumatoid arthritis or psoriasis below the age of 18 have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Neoral · Geriatric Use

  “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.