Digoxin

دیگوکسین

⚠ Unverified

❤️ Cardiovascular SystemCardiac glycoside

Market / country: 🇺🇸 USA

Lanoxin (US)

🧮 Dose calculator

Heart failure · Regimen source: FDA Digoxin · 2.2FDA Digoxin · 2.1FDA Digoxin · 2.4

⛔ Narrow therapeutic range; dose by lean body weight, renal function, age and co-medication. Total oral loading: 5–10 y 20–45 mcg/kg; >10 y and adults 10–15 mcg/kg — half first, then ¼ every 6–8 h twice. Use oral solution for infants. FDA Digoxin · 2.2FDA Digoxin · 2.1FDA Digoxin · 2.4

🛡️ Safety & information

Contraindications

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Digoxin · 8.1

    “Risk Summary Experience with digoxin in pregnant women over several decades, based on published retrospective clinical studies and case reports, has not led to the identification of a drug associated risk of major birth defects, miscarriage or adverse maternal and fetal outcomes.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Digoxin · 8.2

    “Risk Summary The digoxin dose received through breastfeeding is up to 4% of the neonatal maintenance dosage, which is unlikely to be clinically relevant.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Digoxin · 8.4

    “The safety and effectiveness of digoxin tablets in the control of ventricular rate in children with atrial fibrillation have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Digoxin · 8.5

    “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, which should be based on renal function, and it may be useful to monitor renal function [see Dosage and Administration (2.1) ] .”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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