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Digoxin
دیگوکسین
❤️ Cardiovascular SystemCardiac glycoside
🤰 Pregnancy:Use with caution🤱 Breastfeeding:Use with caution👶 Children:Safety not established👴 Older adults:Use with caution 🇮🇷 Registered in Iran⛔ 1 contraindications 🇺🇸 FDA approved generic (ANDA) ANDA078556ATC C01AA05
Market / country: 🇺🇸 USA
Lanoxin (US)
🧮 Dose calculator
Heart failure · Regimen source: FDA Digoxin · 2.2FDA Digoxin · 2.1FDA Digoxin · 2.4
⛔ Narrow therapeutic range; dose by lean body weight, renal function, age and co-medication. Total oral loading: 5–10 y 20–45 mcg/kg; >10 y and adults 10–15 mcg/kg — half first, then ¼ every 6–8 h twice. Use oral solution for infants. FDA Digoxin · 2.2FDA Digoxin · 2.1FDA Digoxin · 2.4
🛡️ Safety & information
Contraindications
- ⛔ Ventricular fibrillation; hypersensitivity to digoxin. FDA Digoxin · 4
Formulations
- 125 mcg tablet (scored) — tablet 🇺🇸 USA FDA Digoxin · 3
- 250 mcg tablet (scored) — tablet 🇺🇸 USA FDA Digoxin · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Digoxin · 8.1
“Risk Summary Experience with digoxin in pregnant women over several decades, based on published retrospective clinical studies and case reports, has not led to the identification of a drug associated risk of major birth defects, miscarriage or adverse maternal and fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Digoxin · 8.2
“Risk Summary The digoxin dose received through breastfeeding is up to 4% of the neonatal maintenance dosage, which is unlikely to be clinically relevant.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Digoxin · 8.4
“The safety and effectiveness of digoxin tablets in the control of ventricular rate in children with atrial fibrillation have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Digoxin · 8.5
“Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, which should be based on renal function, and it may be useful to monitor renal function [see Dosage and Administration (2.1) ] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA078556
- DailyMed (FDA label)FDA Digoxin
- MedlinePlus (NIH)Digoxin
- WHO ATC/DDDC01AA05
- Darooyab (Iran)Digoxin
🇮🇷 Registered in Iran Darooyab · G-1638/Digoxin
Dosage forms with Iranian generic codes, per Darooyab.
- 00439 · DIGOXIN 0.05MG/ML 60ML ELIXIR · الگزیر دیگوکسین ۰٫۰۵ میلیگرم / میلیلیتر ۶۰ میلیلیتر
- 00437 · DIGOXIN 0.05MG/ML ORAL DROP · قطره خوراکی دیگوکسین ۰٫۰۵ میلیگرم / میلیلیتر
- 18338 · DIGOXIN 0.125 MG TAB. · قرص دیگوکسین ۰٫۱۲۵ میلیگرم .
- 00436 · DIGOXIN 0.25MG TAB · قرص دیگوکسین ۰٫۲۵ میلیگرم
- 15447 · DIGOXIN 0.25MG/1ML AMP · آمپول دیگوکسین ۰٫۲۵ میلیگرم / ۱ میلیلیتر
- 00438 · DIGOXIN 0.5MG/2ML AMP · آمپول دیگوکسین ۰٫۵ میلیگرم / ۲ میلیلیتر
- 11506 · DIGOXIN IMMUNE FAB 40MG VIAL · ویال دیگوکسین ایمنی فاب ۴۰ میلیگرم
- 52047 · DIGOXIN INJECTION PARENTERAL 0.25 mg/1mL 1 mL · فرآورده تزریقی دیگوکسین ۰٫۲۵ میلیگرم / ۱ میلیلیتر ۱ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Digoxin · 3FDA Digoxin · 2.2FDA Digoxin · 2.1FDA Digoxin · 2.4FDA Digoxin · 4FDA Digoxin · 8.1FDA Digoxin · 8.2FDA Digoxin · 8.4FDA Digoxin · 8.5FDA Digoxin · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1638/Digoxin
- Clinical review⚠ Unverified