Erlotinib
ارلوتینیب
🎗️ Antineoplastic And Immunomodulating AgentsEGFR inhibitor
Market / country: 🇺🇸 USA
Tarceva (US)
🧮 Dose calculator
Lung cancer (small-cell and non-small-cell) · Regimen source: FDA Erlotinib · 2.2
- • Only under an oncologist; continue until progression or unacceptable toxicity. Dose adjustments for toxicity and interactions per label. FDA Erlotinib · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Warnings
- • Interstitial lung disease; renal failure; hepatotoxicity; GI perforation; bullous skin disorders; stroke; microangiopathic haemolytic anaemia; ocular disorders; bleeding with warfarin; embryo-fetal toxicity. FDA Erlotinib · 5
Formulations
- 25 mg tablet — tablet 🇺🇸 USA FDA Erlotinib · 3
- 100 mg tablet — tablet 🇺🇸 USA FDA Erlotinib · 3
- 150 mg tablet — tablet 🇺🇸 USA FDA Erlotinib · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Erlotinib · 8.1
“Risk Summary Based on animal data and its mechanism of action, erlotinib can cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Erlotinib · 8.2
“Advise a lactating woman not to breastfeed during treatment with erlotinib tablets and for 2 weeks after the final dose.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Erlotinib · 8.4
“The safety and effectiveness of erlotinib in pediatric patients have not been established.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Erlotinib · 8.5
“No overall differences in safety or efficacy were observed between subjects 65 years and older and those younger than 65.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Erlotinib · 8.3
“Contraception Females Erlotinib can cause fetal harm when administered to a pregnant woman [see Use in Specific Populations ( 8.1 )] .”
🔗 Reference links
- FDA (approval record)ANDA091059
- DailyMed (FDA label)FDA Erlotinib
- MedlinePlus (NIH)Erlotinib
- WHO ATC/DDDL01EB02
- Darooyab (Iran)Erlotinib
🇮🇷 Registered in Iran Darooyab · G-4743/Erlotinib
Dosage forms with Iranian generic codes, per Darooyab.
- 14887 · ERLOTINIB 100MG TAB · قرص ارلوتینیب ۱۰۰ میلیگرم
- 06154 · ERLOTINIB 150MG TAB · قرص ارلوتینیب ۱۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Erlotinib · 3FDA Erlotinib · 2.2FDA Erlotinib · 2.3FDA Erlotinib · 5FDA Erlotinib · SPL approval / marketing categoryFDA Erlotinib · 8.1FDA Erlotinib · 8.2FDA Erlotinib · 8.4FDA Erlotinib · 8.5FDA Erlotinib · 8.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-4743/Erlotinib
- Clinical review⚠ Unverified