Gliclazide
گلیکلازید
🍽️ Alimentary Tract And MetabolismSulfonylurea
Market / country: 🇬🇧 UK
Diamicron (GB) · Diamicron MR (GB)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: UK SmPC Diamicron 80 · 4.2
- • Increase until controlled; total 40–320 mg/day. A single dose must not exceed 160 mg; higher doses twice daily with main meals. UK SmPC Diamicron 80 · 4.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to gliclazide, other sulfonylureas or sulfonamides; type 1 diabetes; diabetic ketoacidosis or coma; severe renal or hepatic insufficiency; miconazole; lactation. UK SmPC Diamicron 80 · 4.3UK SmPC Gliclazide MR 30 · 4.3
Warnings
- • Risk of hypoglycaemia; regular meals needed. UK SmPC Diamicron 80 · 4.4
Formulations
- 80 mg tablet (cross-scored) — tablet 🇬🇧 UK UK SmPC Diamicron 80 · 3
- 30 mg modified-release tablet — tablet 🇬🇧 UK UK SmPC Gliclazide MR 30 · 2
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. UK SmPC Diamicron 80 · 4.6
“: There is no or limited amount of data (less than 300 pregnancy outcomes) from the use of gliclazide in pregnant women, even though there are few data with other sulfonylureas.”
- 🤱 BreastfeedingContraindicated
Label: contraindicated while breastfeeding. UK SmPC Diamicron 80 · 4.3
“… patic insufficiency: in these cases the use of insulin is recommended, • Treatment with miconazole (see section 4.5), • Lactation (see section 4.6).”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. UK SmPC Diamicron 80 · 4.2
“Paediatric population The safety and efficacy of Diamicron 80 mg in children and adolescents have not been established.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. UK SmPC Diamicron 80 · 4.2
“Elderly Diamicron 80 mg should be prescribed using the same dosing regimen recommended for patients under 65 years of age.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)❌ None
- DailyMed (FDA label)❌ None
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDA10BB09
- Darooyab (Iran)Gliclazide
- eMC (UK label)UK SmPC Diamicron 80
- eMC (UK label)UK SmPC Gliclazide MR 30
🇮🇷 Registered in Iran Darooyab · G-627/Gliclazide
Dosage forms with Iranian generic codes, per Darooyab.
- 01523 · GLICLAZIDE 80MG TAB · قرص گلیکلازید ۸۰ میلیگرم
- 05442 · GLICLAZIDE SR 30MG TAB · قرص آهستهرهش گلیکلازید ۳۰ میلیگرم
- 19418 · GLICLAZIDE SR 60MG TAB · قرص آهستهرهش گلیکلازید ۶۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)❌ Not present
- UK SmPC (eMC / MHRA)✅ PresentUK SmPC Diamicron 80 · 3UK SmPC Gliclazide MR 30 · 2UK SmPC Diamicron 80 · 4.2UK SmPC Gliclazide MR 30 · 4.2UK SmPC Diamicron 80 · 4.3UK SmPC Gliclazide MR 30 · 4.3UK SmPC Diamicron 80 · 4.4UK SmPC Diamicron 80 · 4.6
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-627/Gliclazide
- Clinical review⚠ Unverified