Ketorolac (injection)
کتورولاک (تزریقی)
🦴 Musculo-Skeletal SystemInjectable NSAID
Market / country: 🇺🇸 USA
Toradol (US)
🧮 Dose calculator
Mild to moderate pain · Regimen source: FDA Ketorolac inj. · Dosage and Administration
- • ≥65 y, renal impairment or <50 kg: 30 mg IM. IV: 30 mg (or 15 mg in those groups). FDA Ketorolac inj. · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Not indicated for pediatric patients. FDA Ketorolac inj. · Boxed Warning
- ⚠️ Boxed warning: GI bleeding/ulceration, CV thrombotic events, renal risk, bleeding; max 5 days; contraindicated in advanced renal impairment and volume depletion. FDA Ketorolac inj. · Boxed Warning
Formulations
- 30 mg/mL injection — injection 🇺🇸 USA FDA Ketorolac inj. · How Supplied
- 15 mg/mL injection — injection 🇺🇸 USA FDA Ketorolac inj. · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Ketorolac inj. · Precautions/Warnings – Pregnancy
“Clinical Considerations Fetal/Neonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including ketorolac tromethamine, can cause premature closure of the fetal ductus arteriosus (see WARNINGS;”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ketorolac inj. · Precautions/Warnings – Nursing Mothers
“Limited data from one published study that included 10 breastfeeding women 2-6 days postpartum showed low levels of ketorolac in breast milk and were undetectable (less than 5 ng/mL) in 4 of the patients.”
- 👶 ChildrenDangerous / avoid
Boxed warning in the label about children. FDA Ketorolac inj. · Boxed Warning
“Ketorolac tromethamine is not indicated for use in pediatric patients and it is NOT indicated for minor or chronic painful conditions.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ketorolac inj. · Boxed Warning
“Elderly patients are at greater risk for serious gastrointestinal events (see WARNINGS ).”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA221041
- DailyMed (FDA label)FDA Ketorolac inj.
- MedlinePlus (NIH)KetorolacKetorolac Injection
- WHO ATC/DDDM01AB15
- Darooyab (Iran)Ketorolac
🇮🇷 Registered in Iran Darooyab · G-110/Ketorolac
Dosage forms with Iranian generic codes, per Darooyab.
- 13573 · KETOROLAC 10MG TAB · قرص کتورولاک ۱۰ میلیگرم
- 17265 · KETOROLAC 10MG/ML INJ · فرآورده تزریقی کتورولاک ۱۰ میلیگرم / میلیلیتر
- 13267 · KETOROLAC 30MG/ML INJ · فرآورده تزریقی کتورولاک ۳۰ میلیگرم / میلیلیتر
- 17972 · KETOROLAC 60MG/2ML INJ · فرآورده تزریقی کتورولاک ۶۰ میلیگرم / ۲ میلیلیتر
- 11458 · KETOROLAC TROMETAMIN 0.5% 5ML OPH DROP · قطره چشمی کتورولاک ترومتامین ۰٫۵ درصد ۵ میلیلیتر
- 23124 · KETOROLAC TROMETAMOL INJECTION PARENTERAL 15 mg/1mL 1 mL · فرآورده تزریقی کتورولاک ترومتامول ۱۵ میلیگرم / ۱ میلیلیتر ۱ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ketorolac inj. · How SuppliedFDA Ketorolac inj. · Dosage and AdministrationFDA Ketorolac inj. · Boxed WarningFDA Ketorolac inj. · Precautions/Warnings – PregnancyFDA Ketorolac inj. · Precautions/Warnings – Nursing MothersFDA Ketorolac inj. · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-110/Ketorolac
- Clinical review⚠ Unverified