Metoprolol tartrate
متوپرولول
❤️ Cardiovascular SystemBeta-1 selective blocker
Market / country: 🇺🇸 USA
Lopressor (US)
🧮 Dose calculator
Hypertension · Regimen source: FDA Metoprolol tartrate · 2.1
- • Effective range 100–450 mg/day; above 450 not studied. With food. FDA Metoprolol tartrate · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Severe bradycardia, second- or third-degree block, cardiogenic shock, systolic BP <100, decompensated heart failure, sick sinus syndrome (no pacemaker), hypersensitivity. FDA Metoprolol tartrate · 4
Formulations
- 25 mg tablet (scored) — tablet 🇺🇸 USA FDA Metoprolol tartrate · 3
- 50 mg tablet (scored) — tablet 🇺🇸 USA FDA Metoprolol tartrate · 3
- 100 mg tablet (scored) — tablet 🇺🇸 USA FDA Metoprolol tartrate · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Metoprolol tartrate · 8.1
“Risk Summary Available data from published observational studies have not demonstrated an association of adverse developmental outcomes with maternal use of metoprolol during pregnancy ( see Data).”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Metoprolol tartrate · 8.2
“Risk Summary Limited available data from published literature report that metoprolol is present in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Metoprolol tartrate · 8.4
“Safety and effectiveness of metoprolol tartrate have not been established in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Metoprolol tartrate · 8.5
“Clinical studies of metoprolol tartrate in hypertension did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Metoprolol tartrate · 8.3
“In animal fertility studies, metoprolol has been associated with reversible adverse effects on spermatogenesis starting at oral dose level of 3.5 mg/kg in rats, which would correspond to a dose of 34 mg/day in humans in mg/m 2 equivalent, although other studies have shown no effect of metoprolol on reproductive …”
🔗 Reference links
- FDA (approval record)ANDA202871
- DailyMed (FDA label)FDA Metoprolol tartrate
- MedlinePlus (NIH)HydrochlorothiazideMetoprolol
- WHO ATC/DDDC07AB02
- Darooyab (Iran)Metoprolol
🇮🇷 Registered in Iran Darooyab · G-1767/Metoprolol
Dosage forms with Iranian generic codes, per Darooyab.
- 11873 · METOPROLOL SUCCINATE 190MG TAB · قرص متوپرولول سوکسینات ۱۹۰ میلیگرم
- 16112 · METOPROLOL SUCCINATE 23.75MG TAB · قرص متوپرولول سوکسینات ۲۳٫۷۵ میلیگرم
- 11871 · METOPROLOL SUCCINATE 47.5MG TAB · قرص متوپرولول سوکسینات ۴۷٫۵ میلیگرم
- 11872 · METOPROLOL SUCCINATE 95MG TAB · قرص متوپرولول سوکسینات ۹۵ میلیگرم
- 02036 · METOPROLOL TARTRATE 100MG TAB · قرص متوپرولول تارتارات ۱۰۰ میلیگرم
- 08514 · METOPROLOL TARTRATE 200MG SR TAB · قرص آهستهرهش متوپرولول تارتارات ۲۰۰ میلیگرم
- 02319 · METOPROLOL TARTRATE 50MG TAB · قرص متوپرولول تارتارات ۵۰ میلیگرم
- 02073 · METOPROLOL TARTRATE 5MG/5ML AMP · آمپول متوپرولول تارتارات ۵ میلیگرم / ۵ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Metoprolol tartrate · 3FDA Metoprolol tartrate · 2.1FDA Metoprolol tartrate · 2.2FDA Metoprolol tartrate · 2.3FDA Metoprolol tartrate · 8.4FDA Metoprolol tartrate · 4FDA Metoprolol tartrate · 8.1FDA Metoprolol tartrate · 8.2FDA Metoprolol tartrate · 8.5FDA Metoprolol tartrate · 8.3FDA Metoprolol tartrate · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1767/Metoprolol
- Clinical review⚠ Unverified