Metoprolol tartrate

متوپرولول

⚠ Unverified

❤️ Cardiovascular SystemBeta-1 selective blocker

Market / country: 🇺🇸 USA

Lopressor (US)

🧮 Dose calculator

Hypertension · Regimen source: FDA Metoprolol tartrate · 2.1

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Severe bradycardia, second- or third-degree block, cardiogenic shock, systolic BP <100, decompensated heart failure, sick sinus syndrome (no pacemaker), hypersensitivity. FDA Metoprolol tartrate · 4

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Metoprolol tartrate · 8.1

    “Risk Summary Available data from published observational studies have not demonstrated an association of adverse developmental outcomes with maternal use of metoprolol during pregnancy ( see Data).”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Metoprolol tartrate · 8.2

    “Risk Summary Limited available data from published literature report that metoprolol is present in human milk.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Metoprolol tartrate · 8.4

    “Safety and effectiveness of metoprolol tartrate have not been established in pediatric patients.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Metoprolol tartrate · 8.5

    “Clinical studies of metoprolol tartrate in hypertension did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Metoprolol tartrate · 8.3

    “In animal fertility studies, metoprolol has been associated with reversible adverse effects on spermatogenesis starting at oral dose level of 3.5 mg/kg in rats, which would correspond to a dose of 34 mg/day in humans in mg/m 2 equivalent, although other studies have shown no effect of metoprolol on reproductive …”

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