Rivaroxaban

🧮 Dose calculator

Atrial fibrillation / anticoagulation · Regimen source: FDA Xarelto · 2.1

• • 15 or 20 mg depending on creatinine clearance. 15 and 20 mg tablets with food. FDA Xarelto · 2FDA Xarelto · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Xarelto · 8.1

  “Risk Summary The limited available data on XARELTO in pregnant women are insufficient to inform a drug-associated risk of adverse developmental outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Xarelto · 8.2

  “Risk Summary Rivaroxaban has been detected in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Xarelto · 8.4

  “The safety and effectiveness of XARELTO have been established in pediatric patients from birth to less than 18 years for the treatment of VTE and the reduction in risk of recurrent VTE.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Xarelto · 8.5

  “Of the total number of adult patients in clinical trials for the approved indications of XARELTO (N=64,943 patients), 64 percent were 65 years and over, with 27 percent 75 years and over.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Xarelto · 8.3

  “Females of reproductive potential requiring anticoagulation should discuss pregnancy planning with their physician.”