Warfarin

🧮 Dose calculator

Atrial fibrillation / anticoagulation · Regimen source: FDA Warfarin · 2.3FDA Warfarin · 2

👥 Special populations

• 🤰 PregnancyContraindicated

  Label: contraindicated in pregnancy. FDA Warfarin · 4

  “Warfarin sodium tablets, USP are contraindicated in: • Pregnancy Warfarin sodium tablets, USP are contraindicated in women who are pregnant except in pregnant women with mechanical heart valves, who are at high risk of thromboembolism [see Warnings and Precautions (5.7) and Use in Specific Populations (8.1) ].”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Warfarin · 8.2

  “Risk Summary Warfarin was not present in human milk from mothers treated with warfarin from a limited published study.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Warfarin · 8.4

  “Adequate and well-controlled studies with warfarin sodium have not been conducted in any pediatric population, and the optimum dosing, safety, and efficacy in pediatric patients is unknown.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Warfarin · 8.5

  “Conduct more frequent monitoring for bleeding with administration of warfarin sodium to elderly patients in any situation or with any physical condition where added risk of hemorrhage is present.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Warfarin · 8.3

  “Contraception Females Advise females of reproductive potential to use effective contraception during treatment and for at least 1 month after the final dose of warfarin sodium.”