Schizophrenia

Schizophrenia · ICD-10: F20.9

Symptoms

  • • Hearing or seeing things that are not there (hallucinations)
  • • Strongly held beliefs that are not real (delusions)
  • • Talking in a way that does not make sense
  • • Isolation
  • • Reduced emotional expression
  • • Trouble concentrating and making decisions
  • • Trouble sleeping
  • • Irritable or tense feelings

MedlinePlus · Symptoms

Drugs and regimens

Aripiprazole⚠ Unverified

Schizophrenia — 13–17 y: target 10 mg

Aripiprazole⚠ Unverified

Schizophrenia — adults: 10 or 15 mg daily

Asenapine⚠ Unverified

Schizophrenia, adults — 5 mg sublingually twice daily (max 10 mg twice daily)

Brexpiprazole⚠ Unverified

Adult schizophrenia — 1 mg days 1–4, 2 mg days 5–7, then up to 4 mg

Cariprazine⚠ Unverified

Adult schizophrenia — start 1.5 mg, range 1.5–6 mg once daily

Chlorpromazine⚠ Unverified

Psychosis — individualised (200 mg/day not unusual)

Clozapine⚠ Unverified

Treatment-resistant schizophrenia — start 12.5 mg once or twice daily

Iloperidone⚠ Unverified

Schizophrenia, adults — target 6–12 mg twice daily after titrating from 1 mg twice daily

Loxapine⚠ Unverified

Schizophrenia, adults — start 10 mg twice daily

Lumateperone⚠ Unverified

Schizophrenia, adults — 42 mg once daily (no titration)

Lurasidone⚠ Unverified

Schizophrenia — adult 40 mg once daily (40–160 mg)

Lurasidone⚠ Unverified

Schizophrenia, adolescents 13–17 y — 40 mg once daily (max 80 mg)

Olanzapine⚠ Unverified

Schizophrenia — 13–17 y: start 2.5 or 5 mg, target 10

Olanzapine⚠ Unverified

Schizophrenia — adults: 5–10 mg, target 10

Paliperidone⚠ Unverified

Schizophrenia — adult 6 mg once daily (3–12 mg)

Paliperidone⚠ Unverified

Schizophrenia, adolescents 12–17 y — 3 mg once daily (max 6 mg <51 kg, 12 mg ≥51 kg)

Perphenazine⚠ Unverified

Outpatient schizophrenia — 4–8 mg three times daily

Quetiapine⚠ Unverified

Schizophrenia — 13–17 y: day 1 25 mg twice daily

Quetiapine⚠ Unverified

Schizophrenia — adults: day 1 25 mg twice daily

Risperidone⚠ Unverified

Schizophrenia — adolescents 13 to 17 years

Risperidone⚠ Unverified

Schizophrenia — adults

Trifluoperazine⚠ Unverified

Schizophrenia — start 2–5 mg twice daily

Trifluoperazine⚠ Unverified

Schizophrenia — 6–12 y (supervised): 1 mg once or twice daily

Ziprasidone⚠ Unverified

Schizophrenia — 20 mg twice daily with food

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