Olanzapine

🧮 Dose calculator

Schizophrenia · Regimen source: FDA Zyprexa · 2.1

• • Weight gain and dyslipidemia are greater in adolescents; other drugs may be considered first. FDA Zyprexa · 1.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Zyprexa · 8.1

  “Risk Summary Neonates exposed to antipsychotic drugs, including ZYPREXA, during the third trimester are at risk for extrapyramidal and/or withdrawal symptoms following delivery (see Clinical Considerations) .”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Zyprexa · 8.2

  “Risk Summary Olanzapine is present in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Zyprexa · 8.4

  “Safety and efficacy of ZYPREXA and fluoxetine in combination in children and adolescents (10 to 17 years of age) have been established for the acute treatment of depressive episodes associated with bipolar I disorder.”

• 👴 Older adultsDangerous / avoid

  Label: serious warning or avoid in older adults. FDA Zyprexa · Boxed Warning

  “Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Zyprexa · 8.3

  “Infertility Females Based on the pharmacologic action of olanzapine (D 2 receptor antagonism), treatment with ZYPREXA may result in an increase in serum prolactin levels, which may lead to a reversible reduction in fertility in females of reproductive potential [see Warnings and Precautions ( 5.15 )] .”