Colesevelam

🧮 Dose calculator

Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Welchol · 2.2

• • Or one 3.75 g packet daily. Check triglycerides first; separate other drugs per label. FDA Welchol · 2.2FDA Welchol · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyNo specific problem stated

  Label: minimal systemic absorption; fetal exposure not expected. FDA Welchol · 8.1

  “Risk Summary WELCHOL is not absorbed systemically following oral administration, and maternal use is not expected to result in fetal exposure to the drug.”

• 🤱 BreastfeedingNo specific problem stated

  Label: infant exposure not expected. FDA Welchol · 8.2

  “Risk Summary WELCHOL is not absorbed systemically by the mother following oral administration, and breastfeeding is not expected to result in exposure of the child to WELCHOL.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Welchol · 8.4

  “Primary Hyperlipidemia The safety and effectiveness of WELCHOL to reduce LDL-C levels in boys and postmenarchal girls 10 to 17 years of age with HeFH who are unable to reach LDL-C target levels despite an adequate trial of dietary therapy and lifestyle modification have been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Welchol · 8.5

  “Primary Hyperlipidemia Of the 1350 patients enrolled in the hyperlipidemia clinical studies, 349 (26%) were ≥65 years old, and 58 (4%) were ≥75 years old.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Welchol · 8.3

  “Contraception Use of WELCHOL may reduce the efficacy of oral contraceptives.”