Niacin (extended-release)

نیاسین (آهسته‌رهش)

⚠ Unverified

❤️ Cardiovascular SystemLipid-modifying agent (nicotinic acid)

Market / country: 🇺🇸 USA

Niaspan (US)

🧮 Dose calculator

Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Niacin ER · 2.1FDA Niacin ER · 2.2

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Active liver disease or unexplained transaminase elevation; active peptic ulcer; arterial bleeding; hypersensitivity. FDA Niacin ER · 4

Warnings

  • • No reduction in cardiovascular events; myopathy (especially with statins); liver injury; raised glucose and uric acid; flushing. FDA Niacin ER · 5

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Niacin ER · 8.1

    “Risk Summary Discontinue niacin extended-release when pregnancy is recognized in patients receiving the drug for the treatment of hyperlipidemia.”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Niacin ER · 8.2

    “Because of the potential for serious adverse reactions in breastfeeding infants, including hepatotoxicity, advise patients not to breastfeed during treatment with niacin extended-release.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Niacin ER · 8.4

    “Safety and effectiveness of niacin therapy in pediatric patients (≤ 16 years) have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Niacin ER · 8.5

    “Of 979 patients in clinical studies of niacin extended-release, 21% of the patients were age 65 and over.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

Shows which sources have references recorded for this drug and which do not.

🔗 Similar drugs

Doz is only a support tool and does not replace clinical judgment or official sources. Check every dose against the original source before prescribing. About & disclaimer · Sources

Information on this site is compiled from online websites and references. Doz accepts no responsibility for self-medication without approval from a physician and a reliable reference, or for any consequences of using this information.

Inspired by the Saphira project; part of the content is taken from it.

For suggestions, corrections, adding drugs or anything else, you can contact me on Telegram: @cenaav