Desflurane

دسفلوران

⚠ Unverified

🧠 Nervous SystemHalogenated inhalational anaesthetic

Market / country: 🇺🇸 USA

Suprane (US)

🧮 Dose calculator

General anaesthesia and premedication (adjunct) · Regimen source: FDA Suprane · 2.3FDA Suprane · 2.2FDA Suprane · 2.6FDA Suprane · 4

⛔ Dosed as concentration %. Adult induction start 3% in 0.5–1% steps; contraindicated for induction in children (airway irritation). Not as sole induction agent in coronary disease. FDA Suprane · 2.3FDA Suprane · 2.2FDA Suprane · 2.6FDA Suprane · 4

🛡️ Safety & information

Contraindications

  • ⛔ Known or suspected genetic susceptibility to malignant hyperthermia; sensitivity to this or other halogenated anaesthetics; induction in children; history of hepatic dysfunction after anaesthesia. FDA Suprane · 4

Warnings

  • • Malignant hyperthermia; perioperative hyperkalaemia (especially myopathies); QT prolongation; hepatic injury; possible neurotoxicity in children under 3 with prolonged anaesthesia. FDA Suprane · 5

Formulations

  • Volatile liquid for dedicated vaporizer (100%) — solution 🇺🇸 USA FDA Suprane · 3

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Suprane · 8.1

    “Risk Summary There are no adequate and well-controlled studies in pregnant women.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Suprane · 8.2

    “Because many drugs are excreted in human milk, caution should be exercised when SUPRANE is administered to a nursing woman.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Suprane · 8.4

    “Respiratory Adverse Reactions in Pediatric Patients SUPRANE is indicated for maintenance of anesthesia in infants and children after induction of anesthesia with agents other than SUPRANE, and tracheal intubation.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Suprane · 8.5

    “The minimum alveolar concentration (MAC) of SUPRANE decreases with increasing patient age.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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