Isoflurane

ایزوفلوران

⚠ Unverified

🧠 Nervous SystemHalogenated inhalational anaesthetic

Market / country: 🇺🇸 USA

Forane (US)

🧮 Dose calculator

General anaesthesia and premedication (adjunct) · Regimen source: FDA Terrell (isoflurane) · 2.3FDA Terrell (isoflurane) · 2.4FDA Terrell (isoflurane) · 2.1

⛔ Dosed as inspired %, not by weight. Induction may cause coughing, breath-holding and laryngospasm. Only with an isoflurane-specific vaporizer. FDA Terrell (isoflurane) · 2.3FDA Terrell (isoflurane) · 2.4FDA Terrell (isoflurane) · 2.1

🛡️ Safety & information

Contraindications

  • ⛔ Known or suspected genetic susceptibility to malignant hyperthermia; sensitivity to this or other halogenated anaesthetics; patients in whom general anaesthesia is contraindicated; prior hepatitis from a halogenated anaesthetic. FDA Terrell (isoflurane) · 4

Warnings

  • • Malignant hyperthermia; perioperative hyperkalaemia (especially myopathies); QT prolongation; hepatic injury; possible neurotoxicity in children under 3 with prolonged anaesthesia. FDA Terrell (isoflurane) · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Terrell (isoflurane) · 8.1

    “Risk Summary There are no adequate and well-controlled studies in pregnant women.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Terrell (isoflurane) · 8.2

    “Due to insufficient information regarding the excretion of isoflurane in human milk, the potential risks and benefits for each specific patient should be carefully considered before isoflurane is administered to nursing women.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Terrell (isoflurane) · 8.4

    “During the induction of anesthesia, saliva flow and tracheobronchial secretion can increase and can be the cause of larynogospasm, particularly in children.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Terrell (isoflurane) · 8.5

    “The minimum alveolar concentration (MAC) of isoflurane decreases with increasing patient age.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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