Domperidone

دومپریدون

⚠ Unverified

🍽️ Alimentary Tract And MetabolismDopamine antagonist; antiemetic

Market / country: 🇬🇧 UK

Motilium (GB)

🧮 Dose calculator

Nausea and vomiting · Regimen source: UK SmPC Domperidone · 4.2

  • • Lowest effective dose for the shortest duration; usually no more than one week. 15–30 min before meals. UK SmPC Domperidone · 4.2

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🛡️ Safety & information

Contraindications

  • ⛔ Known QTc prolongation, significant electrolyte disturbance or underlying cardiac disease; with QT-prolonging drugs or potent CYP3A4 inhibitors. UK SmPC Domperidone · 4.3
  • ⛔ Prolactinoma; phaeochromocytoma; GI haemorrhage, obstruction or perforation; moderate or severe hepatic impairment. UK SmPC Domperidone · 4.3

Warnings

  • • QT prolongation, serious ventricular arrhythmia and sudden cardiac death; higher risk over 60 years and above 30 mg/day. UK SmPC Domperidone · 4.4

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. UK SmPC Domperidone · 4.6

    “There are limited post-marketing data on the use of domperidone in pregnant women.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. UK SmPC Domperidone · 4.6

    “Caution should be exercised in case of QTc prolongation risk factors in breast-fed infants.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. UK SmPC Domperidone · 4.2

    “Paediatric population The efficacy of domperidone in children less than 12 years of age has not been established (see section 5.1).”
  • 👴 Older adultsNo data

    The source for this drug has no section for this group.

  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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