Promethazine (injection)
پرومتازین (آمپول)
🌬️ Respiratory SystemPhenothiazine antihistamine
Market / country: 🇺🇸 USA
Phenergan injection (US)
🧮 Dose calculator
Nausea and vomiting · Regimen source: FDA Promethazine inj. · Dosage and Administration
- • Preferably deep IM; IV use risks severe tissue injury. FDA Promethazine inj. · Boxed Warning
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Contraindicated under 2 years (fatal respiratory depression). FDA Promethazine inj. · Boxed Warning
- ⚠️ Boxed warning: severe tissue injury and gangrene with improper injection; respiratory depression in children. FDA Promethazine inj. · Boxed Warning
Formulations
- 25 mg/mL injection — injection 🇺🇸 USA FDA Promethazine inj. · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Promethazine inj. · Pregnancy Tests
“Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Promethazine inj. · Nursing Mothers
“Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in nursing infants from promethazine hydrochloride injection, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenContraindicated
Label: contraindicated in children below a stated age. FDA Promethazine inj. · CONTRAINDICATIONS
“The use of promethazine hydrochloride injection is contraindicated: In pediatric patients less than 2 years of age due to the risk of respiratory depression (see WARNINGS – Respiratory Depression ).”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Promethazine inj. · Geriatric Use (patients approximately 60 years or older)
“Since therapeutic requirements for sedative drugs tend to be less in geriatric patients, the dosage should be reduced for these patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA083312
- DailyMed (FDA label)FDA Promethazine inj.
- MedlinePlus (NIH)Promethazine
- WHO ATC/DDDR06AD02
- Darooyab (Iran)Promethazine
🇮🇷 Registered in Iran Darooyab · G-822/Promethazine
Dosage forms with Iranian generic codes, per Darooyab.
- 10253 · PROMETHAZINE 10MG TAB · قرص پرومتازین ۱۰ میلیگرم
- 02095 · PROMETHAZINE 25MG/ML 1ML AMP · آمپول پرومتازین ۲۵ میلیگرم / میلیلیتر ۱ میلیلیتر
- 01061 · PROMETHAZINE 50MG/2ML AMP · آمپول پرومتازین ۵۰ میلیگرم / ۲ میلیلیتر
- 01060 · PROMETHAZINE 5MG/5ML 60ML SYRUP · شربت پرومتازین ۵ میلیگرم / ۵ میلیلیتر ۶۰ میلیلیتر
- 01062 · PROMETHAZINE HCL 25MG TAB · قرص پرومتازین هیدروکلراید ۲۵ میلیگرم
- 50433 · PROMETHAZINE HYDROCHLORIDE INJECTION PARENTERAL 25 mg/1mL 2 mL · فرآورده تزریقی پرومتازین هیدروکلراید ۲۵ میلیگرم / ۱ میلیلیتر ۲ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Promethazine inj. · How SuppliedFDA Promethazine inj. · Dosage and AdministrationFDA Promethazine inj. · Boxed WarningFDA Promethazine inj. · Pregnancy TestsFDA Promethazine inj. · Nursing MothersFDA Promethazine inj. · CONTRAINDICATIONSFDA Promethazine inj. · Geriatric Use (patients approximately 60 years or older)FDA Promethazine inj. · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-822/Promethazine
- Clinical review⚠ Unverified