Domperidone
دومپریدون
🍽️ Alimentary Tract And MetabolismDopamine antagonist; antiemetic
Market / country: 🇬🇧 UK
Motilium (GB)
🧮 Dose calculator
Nausea and vomiting · Regimen source: UK SmPC Domperidone · 4.2
- • Lowest effective dose for the shortest duration; usually no more than one week. 15–30 min before meals. UK SmPC Domperidone · 4.2
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Known QTc prolongation, significant electrolyte disturbance or underlying cardiac disease; with QT-prolonging drugs or potent CYP3A4 inhibitors. UK SmPC Domperidone · 4.3
- ⛔ Prolactinoma; phaeochromocytoma; GI haemorrhage, obstruction or perforation; moderate or severe hepatic impairment. UK SmPC Domperidone · 4.3
Warnings
- • QT prolongation, serious ventricular arrhythmia and sudden cardiac death; higher risk over 60 years and above 30 mg/day. UK SmPC Domperidone · 4.4
Formulations
- 1 mg / mL oral suspension — suspension 🇬🇧 UK UK SmPC Domperidone · 1
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. UK SmPC Domperidone · 4.6
“There are limited post-marketing data on the use of domperidone in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. UK SmPC Domperidone · 4.6
“Caution should be exercised in case of QTc prolongation risk factors in breast-fed infants.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. UK SmPC Domperidone · 4.2
“Paediatric population The efficacy of domperidone in children less than 12 years of age has not been established (see section 5.1).”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)❌ None
- DailyMed (FDA label)❌ None
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDA03FA03
- Darooyab (Iran)Domperidone
- eMC (UK label)UK SmPC Domperidone
🇮🇷 Registered in Iran Darooyab · G-2576/Domperidone
Dosage forms with Iranian generic codes, per Darooyab.
- 11438 · DOMPERIDEN 1MG/200ML SYR · دومپرایدن ۱ میلیگرم / ۲۰۰ میلیلیتر
- 12821 · DOMPERIDONE 10MG CAP · کپسول دومپریدون ۱۰ میلیگرم
- 11520 · DOMPERIDONE 10MG/5ML 300ML SYR · دومپریدون ۱۰ میلیگرم / ۵ میلیلیتر ۳۰۰ میلیلیتر
- 06587 · DOMPERIDONE 1MG/ML SUSP · سوسپانسیون دومپریدون ۱ میلیگرم / میلیلیتر
- 07551 · DOMPERIDONE 5MG/5ML SYRUP · شربت دومپریدون ۵ میلیگرم / ۵ میلیلیتر
- 06754 · DOMPERIDONE MALEATE 10MG TAB · قرص دومپریدون مالئات ۱۰ میلیگرم
- 52038 · DOMPERIDONE SUSPENSION ORAL 1 mg/1 mL 200 mL · سوسپانسیون خوراکی دومپریدون ۱ میلیگرم / ۱ میلیلیتر ۲۰۰ میلیلیتر
- 52673 · DOMPERIDONE SUSPENSION ORAL 1 mg/1 mL 120 mL · سوسپانسیون خوراکی دومپریدون ۱ میلیگرم / ۱ میلیلیتر ۱۲۰ میلیلیتر
- 52039 · DOMPERIDONE SUSPENSION ORAL 1 mg/1 mL 100 mL · سوسپانسیون خوراکی دومپریدون ۱ میلیگرم / ۱ میلیلیتر ۱۰۰ میلیلیتر
- 53039 · DOMPERIDONE SUSPENSION ORAL 1 mg/1 mL 250 mL · سوسپانسیون خوراکی دومپریدون ۱ میلیگرم / ۱ میلیلیتر ۲۵۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)❌ Not present
- UK SmPC (eMC / MHRA)✅ PresentUK SmPC Domperidone · 1UK SmPC Domperidone · 4.2UK SmPC Domperidone · 4.3UK SmPC Domperidone · 4.4UK SmPC Domperidone · 4.6
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2576/Domperidone
- Clinical review⚠ Unverified