Exemestane
اگزمستان
🎗️ Antineoplastic And Immunomodulating AgentsSteroidal aromatase inactivator
Market / country: 🇺🇸 USA
Aromasin (US)
🧮 Dose calculator
Breast cancer (hormonal therapy) · Regimen source: FDA Aromasin · 2.1
- • With strong CYP3A4 inducers (rifampin, phenytoin): 50 mg. FDA Aromasin · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to exemestane. FDA Aromasin · 4
Warnings
- • Reduced bone mineral density; check vitamin D; not with oestrogens; not for premenopausal women; embryo-fetal toxicity. FDA Aromasin · 5
Formulations
- 25 mg tablet — tablet 🇺🇸 USA FDA Aromasin · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Aromasin · 8.1
“Risk Summary Based on findings in animal studies and its mechanism of action , AROMASIN can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology (12.1) ] .”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Aromasin · 8.2
“Risk Summary There is no information on the presence of exemestane in human milk, or on its effects on the breastfed infant or milk production.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Aromasin · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Aromasin · 8.3
“Contraception Females AROMASIN can cause fetal harm when administered to a pregnant woman [see Use in Specific Populations (8.1) ] .”
🔗 Reference links
- FDA (approval record)NDA020753
- DailyMed (FDA label)FDA Aromasin
- MedlinePlus (NIH)Exemestane
- WHO ATC/DDDL02BG06
- Darooyab (Iran)Exemestane
🇮🇷 Registered in Iran Darooyab · G-997/Exemestane
Dosage forms with Iranian generic codes, per Darooyab.
- 02962 · EXEMESTANE 25MG TAB · قرص اکسمستان ۲۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Aromasin · 3FDA Aromasin · 2.1FDA Aromasin · 2.2FDA Aromasin · 4FDA Aromasin · 5FDA Aromasin · SPL approval / marketing categoryFDA Aromasin · 8.1FDA Aromasin · 8.2FDA Aromasin · 8.4FDA Aromasin · 8.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-997/Exemestane
- Clinical review⚠ Unverified