Sitagliptin

🧮 Dose calculator

Type 2 diabetes mellitus · Regimen source: FDA Sitagliptin · 2.1

• • eGFR 30 to <45: 50 mg; eGFR <30 or dialysis: 25 mg once daily. FDA Sitagliptin · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Sitagliptin · 8.1

  “Risk Summary The limited available data with sitagliptin tablets in pregnant women are not sufficient to inform a drug- associated risk for major birth defects and miscarriage.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Sitagliptin · 8.2

  “Risk Summary There is no information regarding the presence of sitagliptin in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Sitagliptin · 8.4

  “The safety and effectiveness of sitagliptin have not been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Sitagliptin · 8.5

  “… function should be assessed more frequently in elderly patients [see Dosage and Administration ( 2.2 ), Warnings and Precautions ( 5.3 )] .”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.