Bupropion
بوپروپیون
🧠 Nervous SystemAntidepressant (NDRI)
Market / country: 🇺🇸 USA
Wellbutrin XL (US)
🧮 Dose calculator
Major depressive disorder · Regimen source: FDA Bupropion XL · 2.2
- • Increase gradually to reduce seizure risk; swallow whole. FDA Bupropion XL · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Seizure disorder; current or prior bulimia or anorexia nervosa. FDA Bupropion XL · 4
Formulations
- 150 mg tablet — tablet 🇺🇸 USA FDA Bupropion XL · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Bupropion XL · 8.1
“Risk Summary Data from epidemiological studies of pregnant women exposed to bupropion in the first trimester have not identified an increased risk of congenital malformations overall (see Data).”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Bupropion XL · 8.2
“Risk Summary Data from published literature report the presence of bupropion and its metabolites in human milk (see Data).”
- 👶 ChildrenDangerous / avoid
Boxed warning in the label about children. FDA Bupropion XL · Boxed Warning
“SUICIDALITY AND ANTIDEPRESSANT DRUGS Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Bupropion XL · 8.5
“Because elderly patients are more likely to have decreased renal function, it may be necessary to consider this factor in dose selection; it may be useful to monitor renal function [see Dosage and Administration ( 2.7 ), Use in Specific Populations ( 8.6 ), and Clinical Pharmacology ( 12.3 )] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA077715
- DailyMed (FDA label)FDA Bupropion XL
- MedlinePlus (NIH)Bupropion
- WHO ATC/DDDN06AX12
- Darooyab (Iran)Bupropion
🇮🇷 Registered in Iran Darooyab · G-574/Bupropion
Dosage forms with Iranian generic codes, per Darooyab.
- 01909 · BUPROPION 100MG TAB · قرص بوپروپیون ۱۰۰ میلیگرم
- 01908 · BUPROPION 75MG TAB · قرص بوپروپیون ۷۵ میلیگرم
- 02033 · BUPROPION SR 150MG TAB · قرص آهستهرهش بوپروپیون ۱۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Bupropion XL · 3FDA Bupropion XL · 2.2FDA Bupropion XL · 2.1FDA Bupropion XL · 2.3FDA Bupropion XL · 4FDA Bupropion XL · 8.1FDA Bupropion XL · 8.2FDA Bupropion XL · Boxed WarningFDA Bupropion XL · 8.5FDA Bupropion XL · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-574/Bupropion
- Clinical review⚠ Unverified