Venlafaxine
ونلافاکسین
🧠 Nervous SystemSNRI
Market / country: 🇺🇸 USA
Effexor XR (US)
🧮 Dose calculator
Major depressive disorder · Regimen source: FDA Venlafaxine XR · 2.2
- • Some patients: 37.5 mg for 4–7 days then 75. With food; do not open capsule. FDA Venlafaxine XR · 2.2FDA Venlafaxine XR · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ MAOI (incl. linezolid or IV methylene blue) or within 14 days. FDA Venlafaxine XR · 4
Formulations
- 37.5 mg capsule — capsule 🇺🇸 USA FDA Venlafaxine XR · 3
- 75 mg capsule — capsule 🇺🇸 USA FDA Venlafaxine XR · 3
- 150 mg capsule — capsule 🇺🇸 USA FDA Venlafaxine XR · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Venlafaxine XR · 8.1
“Risk Summary Based on data from published observational studies, exposure to SNRIs, particularly in the month before delivery, has been associated with a less than 2-fold increase in the risk of postpartum hemorrhage [see Warnings and Precautions (5.4) and Clinical Considerations] .”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Venlafaxine XR · 8.2
“Risk Summary Data from published literature report the presence of venlafaxine and its active metabolite in human milk and have not shown adverse reactions in breastfed infants (see Data) .”
- 👶 ChildrenDangerous / avoid
Boxed warning in the label about children. FDA Venlafaxine XR · Boxed Warning
“Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Venlafaxine XR · 8.5
“… ly significant hyponatremia in elderly patients, who may be at greater risk for this adverse event [see Warnings and Precautions (5.9) ] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA200834
- DailyMed (FDA label)FDA Venlafaxine XR
- MedlinePlus (NIH)Venlafaxine
- WHO ATC/DDDN06AX16
- Darooyab (Iran)Venlafaxine
🇮🇷 Registered in Iran Darooyab · G-617/Venlafaxine
Dosage forms with Iranian generic codes, per Darooyab.
- 09557 · VENLAFAXINE 100MCG TAB · قرص ونلافاکسین ۱۰۰ میکروگرم
- 05154 · VENLAFAXINE 150MG EXTENDED RELEASE CAP · کپسول آهستهرهش ونلافاکسین ۱۵۰ میلیگرم
- 09713 · VENLAFAXINE 150MG TAB · قرص ونلافاکسین ۱۵۰ میلیگرم
- 05791 · VENLAFAXINE 37.5MG CAP · کپسول ونلافاکسین ۳۷٫۵ میلیگرم
- 16035 · VENLAFAXINE 37.5MG EXTENDED RELEASE CAP · کپسول آهستهرهش ونلافاکسین ۳۷٫۵ میلیگرم
- 07932 · VENLAFAXINE 37.5MG TAB · قرص ونلافاکسین ۳۷٫۵ میلیگرم
- 14404 · VENLAFAXINE 50MG TAB · قرص ونلافاکسین ۵۰ میلیگرم
- 05155 · VENLAFAXINE 75MG CAP · کپسول ونلافاکسین ۷۵ میلیگرم
- 13873 · VENLAFAXINE 75MG EXTENDED RELEASE CAP · کپسول آهستهرهش ونلافاکسین ۷۵ میلیگرم
- 06631 · VENLAFAXINE 75MG TAB · قرص ونلافاکسین ۷۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Venlafaxine XR · 3FDA Venlafaxine XR · 2.2FDA Venlafaxine XR · 2.1FDA Venlafaxine XR · 4FDA Venlafaxine XR · 8.1FDA Venlafaxine XR · 8.2FDA Venlafaxine XR · Boxed WarningFDA Venlafaxine XR · 8.5FDA Venlafaxine XR · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-617/Venlafaxine
- Clinical review⚠ Unverified