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Trazodone
ترازودون
🧠 Nervous SystemAntidepressant
🤰 Pregnancy:Use with caution🤱 Breastfeeding:Use with caution👶 Children:Dangerous / avoid👴 Older adults:Use with caution 🇮🇷 Registered in Iran⛔ 1 contraindications 🇺🇸 FDA approved generic (ANDA) ANDA218988ATC N06AX05
Market / country: 🇺🇸 USA
Desyrel (US)
🧮 Dose calculator
Major depressive disorder · Regimen source: FDA Trazodone · 2.1
- • Start low and increase gradually; after a meal; if drowsy, give most of the dose at bedtime. FDA Trazodone · 2.1FDA Trazodone · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ MAOI (incl. linezolid or IV methylene blue) or within 14 days. FDA Trazodone · 4
Formulations
- 50 mg tablet — tablet 🇺🇸 USA FDA Trazodone · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Trazodone · 8.1
“Risk Summary Published prospective cohort studies, case series, and case reports over several decades with trazodone hydrochloride tablets use in pregnant women have not identified any drug-associated risks of major birth defects, miscarriage, or adverse maternal or fetal outcomes (see Data) .”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Trazodone · 8.2
“Risk Summary Data from published literature report the transfer of trazodone into human milk.”
- 👶 ChildrenDangerous / avoid
Boxed warning in the label about children. FDA Trazodone · Boxed Warning
“Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients in short-term studies.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Trazodone · 8.5
“However, as experience in the elderly with trazodone hydrochloride is limited, it should be used with caution in geriatric patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA218988
- DailyMed (FDA label)FDA Trazodone
- MedlinePlus (NIH)Trazodone
- WHO ATC/DDDN06AX05
- Darooyab (Iran)Trazodone
🇮🇷 Registered in Iran Darooyab · G-614/Trazodone
Dosage forms with Iranian generic codes, per Darooyab.
- 01864 · TRAZODONE HCL 100MG TAB · قرص ترازودون هیدروکلراید ۱۰۰ میلیگرم
- 01242 · TRAZODONE HCL 50MG TAB · قرص ترازودون هیدروکلراید ۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Trazodone · 3FDA Trazodone · 2.1FDA Trazodone · 2.2FDA Trazodone · 4FDA Trazodone · 8.1FDA Trazodone · 8.2FDA Trazodone · Boxed WarningFDA Trazodone · 8.5FDA Trazodone · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-614/Trazodone
- Clinical review⚠ Unverified