Dapagliflozin
داپاگلیفلوزین
🍽️ Alimentary Tract And MetabolismSGLT2 inhibitor
Market / country: 🇺🇸 USA
Farxiga (US) · Forxiga (GB)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: FDA Farxiga · 2
- • Up to 10 mg for more control. Correct volume depletion first. FDA Farxiga · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ History of serious hypersensitivity to dapagliflozin. FDA Farxiga · 4
- ⛔ Not established under 10 years. FDA Farxiga · 8.4
Formulations
- 5 mg tablet — tablet 🇺🇸 USA FDA Farxiga · 3
- 10 mg tablet — tablet 🇺🇸 USA FDA Farxiga · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Farxiga · 8.1
“Risk Summary Based on animal data showing adverse renal effects, FARXIGA is not recommended during the second and third trimesters of pregnancy.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Farxiga · 8.2
“Risk Summary There is no information regarding the presence of dapagliflozin in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Farxiga · 8.4
“The safety and effectiveness of FARXIGA as an adjunct to diet and exercise to improve glycemic control in type 2 diabetes mellitus have been established in pediatric patients aged 10 years and older.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Farxiga · 8.5
“In patients ≥65 years of age, a higher proportion of patients treated with FARXIGA for glycemic control had adverse reactions of hypotension [see Warnings and Precautions (5.2) and Adverse Reactions (6.1) ] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA202293
- DailyMed (FDA label)FDA Farxiga
- MedlinePlus (NIH)Dapagliflozin
- WHO ATC/DDDA10BK01
- Darooyab (Iran)Dapagliflozin
🇮🇷 Registered in Iran Darooyab · G-5458/Dapagliflozin
Dosage forms with Iranian generic codes, per Darooyab.
- 52201 · DAPAGLIFLOZIN 5MG TAB · قرص داپاگلیفلوزین ۵ میلیگرم
- 52167 · DAPAGLIFLOZIN 10MG TAB · قرص داپاگلیفلوزین ۱۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Farxiga · 3FDA Farxiga · 2FDA Farxiga · 4FDA Farxiga · 8.4FDA Farxiga · 8.1FDA Farxiga · 8.2FDA Farxiga · 8.5FDA Farxiga · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-5458/Dapagliflozin
- Clinical review⚠ Unverified