Empagliflozin
امپاگلیفلوزین
🍽️ Alimentary Tract And MetabolismSGLT2 inhibitor
Market / country: 🇺🇸 USA
Jardiance (US)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: FDA Jardiance · 2.2, Table 1
- • If tolerated may increase to 25 mg for more control. Not recommended for glycaemic control with eGFR <30. Correct volume depletion first. FDA Jardiance · 2.2FDA Jardiance · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to empagliflozin (including angioedema). FDA Jardiance · 4
- ⛔ Not established under 10 years. FDA Jardiance · 8.4
Formulations
- 10 mg tablet — tablet 🇺🇸 USA FDA Jardiance · 3
- 25 mg tablet — tablet 🇺🇸 USA FDA Jardiance · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Jardiance · 8.1
“Risk Summary Based on animal data showing adverse renal effects, JARDIANCE is not recommended during the second and third trimesters of pregnancy.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Jardiance · 8.2
“Risk Summary There is limited information regarding the presence of JARDIANCE in human milk, the effects of JARDIANCE on the breastfed infant or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Jardiance · 8.4
“The safety and effectiveness of JARDIANCE as an adjunct to diet and exercise to improve glycemic control in type 2 diabetes mellitus have been established in pediatric patients aged 10 years and older.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Jardiance · 8.5
“… %, and 15.1% in patients randomized to placebo, JARDIANCE 10 mg, and JARDIANCE 25 mg, respectively [see Warnings and Precautions (5.2) and Adverse Reactions (6.1) ] .”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA204629
- DailyMed (FDA label)FDA Jardiance
- MedlinePlus (NIH)Empagliflozin
- WHO ATC/DDDA10BK03
- Darooyab (Iran)Empagliflozin
🇮🇷 Registered in Iran Darooyab · G-632/Empagliflozin
Dosage forms with Iranian generic codes, per Darooyab.
- 52137 · EMPAGLIFLOZIN 25 MG TABLET · قرص امپاگلیفلوزین ۲۵ میلیگرم
- 52138 · EMPAGLIFLOZIN 10 MG TABLET · قرص امپاگلیفلوزین ۱۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Jardiance · 3FDA Jardiance · 2.2, Table 1FDA Jardiance · 2.2FDA Jardiance · 2FDA Jardiance · 4FDA Jardiance · 8.4FDA Jardiance · 8.1FDA Jardiance · 8.2FDA Jardiance · 8.5FDA Jardiance · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-632/Empagliflozin
- Clinical review⚠ Unverified