Ezetimibe
ازتیمایب
❤️ Cardiovascular SystemCholesterol absorption inhibitor
Market / country: 🇺🇸 USA
Zetia (US)
🧮 Dose calculator
Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Ezetimibe · 2
- • With or without food; 2 h before or 4 h after bile acid sequestrants. Children ≥10 y: HeFH only, with a statin. FDA Ezetimibe · 2FDA Ezetimibe · 8.4
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity; with a statin or fenofibrate, wherever those are contraindicated. FDA Ezetimibe · 4
- ⛔ Not established under 10 years. FDA Ezetimibe · 8.4
Formulations
- 10 mg tablet — tablet 🇺🇸 USA FDA Ezetimibe · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ezetimibe · 8.1
“Risk Summary There are insufficient data on ezetimibe use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ezetimibe · 8.2
“Risk Summary There is no information about the presence of ezetimibe in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ezetimibe · 8.4
“The safety and effectiveness of ezetimibe in combination with a statin as an adjunct to diet to reduce LDL-C have been established in pediatric patients 10 years of age and older with HeFH.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Ezetimibe · 8.5
“No overall differences in safety or effectiveness of ezetimibe have been observed between patients 65 years of age and older and younger patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA208803
- DailyMed (FDA label)FDA Ezetimibe
- MedlinePlus (NIH)Ezetimibe
- WHO ATC/DDDC10AX09
- Darooyab (Iran)Ezetimibe
🇮🇷 Registered in Iran Darooyab · G-1676/Ezetimibe
Dosage forms with Iranian generic codes, per Darooyab.
- 05657 · EZETIMIBE 10MG TAB · قرص ازتیمایب ۱۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ezetimibe · 3FDA Ezetimibe · 2FDA Ezetimibe · 8.4FDA Ezetimibe · 4FDA Ezetimibe · 8.1FDA Ezetimibe · 8.2FDA Ezetimibe · 8.5FDA Ezetimibe · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1676/Ezetimibe
- Clinical review⚠ Unverified