Rosuvastatin

رزوواستاتین

⚠ Unverified

❤️ Cardiovascular SystemStatin (HMG-CoA reductase inhibitor)

Market / country: 🇺🇸 USA

Crestor (US)

🧮 Dose calculator

Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Rosuvastatin · 2.2

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🛡️ Safety & information

Contraindications

  • ⛔ Acute liver failure or decompensated cirrhosis; hypersensitivity. FDA Crestor · 4

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Rosuvastatin · 8.1

    “Rosuvastatin calcium decreases synthesis of cholesterol and possibly other biologically active substances derived from cholesterol; therefore, rosuvastatin calcium may cause fetal harm when administered to pregnant patients based on the mechanism of action [ see Clinical Pharmacology (12.1) ].”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Rosuvastatin · 8.2

    “Because of the potential for serious adverse reactions in a breastfed infant, based on the mechanism of action, advise patients that breastfeeding is not recommended during treatment with rosuvastatin calcium [ see Use in Specific Populations (8.1) and Clinical Pharmacology (12.1) ].”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Rosuvastatin · 8.4

    “The safety and effectiveness of rosuvastatin calcium as an adjunct to diet to reduce LDL-C have been established in pediatric patients 8 years of age and older with HeFH.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Rosuvastatin · 8.5

    “Dose selection for an elderly patient should be cautious, recognizing the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy and the higher risk of myopathy.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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