Spironolactone

🧮 Dose calculator

Heart failure · Regimen source: FDA Spironolactone · 2.2

• • If potassium ≤5.0 and eGFR >50. If tolerated up to 50 mg; with hyperkalemia 25 mg every other day. eGFR 30–50: start every other day. FDA Spironolactone · 2.2FDA Spironolactone · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Spironolactone · 8.1

  “Risk Summary Based on mechanism of action and findings in animal studies, spironolactone may affect sex differentiation of the male during embryogenesis (see Data).”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Spironolactone · 8.2

  “Risk Summary Spironolactone is not present in breastmilk; however, limited data from a lactating woman at 17 days postpartum reports the presence of the active metabolite, canrenone, in human breast milk in low amounts that are expected to be clinically inconsequential.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Spironolactone · 8.4

  “Safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Spironolactone · 8.5

  “Because elderly patients are more likely to have decreased renal function, monitor renal function.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.