Amitriptyline

🧮 Dose calculator

Major depressive disorder · Regimen source: FDA Amitriptyline · Dosage and Administration

• • If needed up to 150 mg/day. Alternative: 50–100 mg at bedtime, increasing by 25–50 mg to 150. Inpatients up to 200 (rarely 300) mg/day. FDA Amitriptyline · Dosage and Administration

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Amitriptyline · Precautions/Warnings – Usage in Pregnancy

  “Amitriptyline hydrochloride should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Amitriptyline · Nursing Mothers

  “Because of the potential for serious adverse reactions in nursing infants from amitriptyline, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”

• 👶 ChildrenDangerous / avoid

  Boxed warning in the label about children. FDA Amitriptyline · Boxed Warning

  “Amitriptyline hydrochloride is not approved for use in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Amitriptyline · Geriatric Use

  “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic function, concomitant disease and other drug therapy in elderly patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.