Carbamazepine
کاربامازپین
🧠 Nervous SystemAnticonvulsant
Market / country: 🇺🇸 USA
Tegretol (US)
🧮 Dose calculator
Epilepsy (complex partial / absence seizures) · Regimen source: FDA Carbamazepine · Dosage and Administration
- • Increase weekly to response; usually below 35 mg/kg/day; tablets 2–3 times daily. FDA Carbamazepine · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ History of bone marrow depression; hypersensitivity to carbamazepine or tricyclics; MAOIs. FDA Carbamazepine · Contraindications
Warnings
- • Boxed warning: fatal skin reactions (SJS/TEN) linked to HLA-B*1502 (about 10× risk in some Asian populations); aplastic anemia and agranulocytosis. FDA Carbamazepine · WARNINGS (boxed): SERIOUS DERMATOLOGIC REACTIONS AND HLA-B*1502 ALLELE
Formulations
- 200 mg tablet (partially scored) — tablet 🇺🇸 USA FDA Carbamazepine · How Supplied
- 100 mg / 5 mL suspension — suspension 🇺🇸 USA FDA Carbamazepine susp. · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Carbamazepine · Precautions/Warnings – Usage in Pregnancy
“Carbamazepine can cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Carbamazepine · Precautions/Warnings – Nursing Mothers
“Because of the potential for serious adverse reactions in nursing infants from carbamazepine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Carbamazepine · Precautions/Warnings – Pediatric Use
“Substantial evidence of carbamazepine's effectiveness for use in the management of children with epilepsy (see INDICATIONS AND USAGE for specific seizure types) is derived from clinical investigations performed in adults and from studies in several in vitro systems which support the conclusion that (1) the …”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Carbamazepine · Precautions/Warnings – Geriatric Use
“No systematic studies in geriatric patients have been conducted.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA207798
- DailyMed (FDA label)FDA CarbamazepineFDA Carbamazepine susp.
- MedlinePlus (NIH)Carbamazepine
- WHO ATC/DDDN03AF01
- Darooyab (Iran)Carbamazepine
🇮🇷 Registered in Iran Darooyab · G-659/Carbamazepine
Dosage forms with Iranian generic codes, per Darooyab.
- 09437 · CARBAMAZEPINE 100MG/5ML 120ML SUSP · سوسپانسیون کاربامازپین ۱۰۰ میلیگرم / ۵ میلیلیتر ۱۲۰ میلیلیتر
- 14911 · CARBAMAZEPINE 100MG/5ML 250ML SYRUP · شربت کاربامازپین ۱۰۰ میلیگرم / ۵ میلیلیتر ۲۵۰ میلیلیتر
- 00208 · CARBAMAZEPINE 200MG TAB · قرص کاربامازپین ۲۰۰ میلیگرم
- 10690 · CARBAMAZEPINE 300MG SR TAB · قرص آهستهرهش کاربامازپین ۳۰۰ میلیگرم
- 02114 · CARBAMAZEPINE SR 200MG TAB · قرص آهستهرهش کاربامازپین ۲۰۰ میلیگرم
- 01420 · CARBAMAZEPINE SR 400MG TAB · قرص آهستهرهش کاربامازپین ۴۰۰ میلیگرم
- 51864 · CARBAMAZEPINE SUSPENSION ORAL 100 mg/5mL 120 mL · سوسپانسیون خوراکی کاربامازپین ۱۰۰ میلیگرم / ۵ میلیلیتر ۱۲۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Carbamazepine · How SuppliedFDA Carbamazepine susp. · How SuppliedFDA Carbamazepine · Dosage and AdministrationFDA Carbamazepine · Dosage and Administration — Trigeminal NeuralgiaFDA Carbamazepine · Indications and UsageFDA Carbamazepine · ContraindicationsFDA Carbamazepine · WARNINGS (boxed): SERIOUS DERMATOLOGIC REACTIONS AND HLA-B*1502 ALLELEFDA Carbamazepine · Precautions/Warnings – Usage in PregnancyFDA Carbamazepine · Precautions/Warnings – Nursing MothersFDA Carbamazepine · Precautions/Warnings – Pediatric UseFDA Carbamazepine · Precautions/Warnings – Geriatric UseFDA Carbamazepine · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-659/Carbamazepine
- Clinical review⚠ Unverified